| Tag |
Content |
| dbPAF ID |
dbPAF-0004539 |
| Uniprot Accession |
P07247; KRUP_DROME; Q8SYW3; Q9W0V9;
|
| Genbank Protein ID |
NP_001261181.1; NP_523867.1;
|
| Genbank Nucleotide ID |
NM_001274252.1; NM_079143.3;
|
| Protein Name |
Protein krueppel |
| Protein Synonyms/Alias |
|
| Gene Name |
Kr |
| Gene Synonyms/Alias |
CG3340; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Krueppel is a gap class segmentation protein. It is involved in the segmentation of the embryo and in the differentiation of the Malpighian tubules.Functional Description
Krueppel is a gap class segmentation protein. It is involved in the segmentation of the embryo and in the differentiation of the Malpighian tubules. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MSISMLQDAQ TRTLAAALAG IKQEDVHLDR SMSLSPPMSA NTSATSAAAI YPAMGLQQAA 60
AASAFGMLSP TQLLAANRQA AAFMAQLPMS TLANTLFPHN PAALFGAWAA QQSLPPQGTH 120
LHSPPASPHS PLSTPLGSGK HPLNSPNSTP QHHEPAKKAR KLSVKKEFQT EISMSVNDMY 180
HTSGGPISPP SSGSSPNSTH DGAGGNAGCV GVSKDPSRDK SFTCKICSRS FGYKHVLQNH 240
ERTHTGEKPF ECPECHKRFT RDHHLKTHMR LHTGEKPYHC SHCDRQFVQV ANLRRHLRVH 300
TGERPYTCEI CDGKFSDSNQ LKSHMLVHNG EKPFECERCH MKFRRRHHLM NHKCGIQSPP 360
TPALSPAMSG DYPVAISAIA IEASTNRFAA MCATYGGSNE SVDMEKATPE DDGPLDLSED 420
GASSVDGHCS NIARRKAQDI RRVFRLPPPQ IPHVPSDMPE QTEPEDLSMH SPRSIGSHEQ 480
TDDIDLYDLD DAPASYMGHQ QH
503Fasta Sequence
>P07247|Kr|Drosophila melanogaster(Fruit fly)
MSISMLQDAQTRTLAAALAGIKQEDVHLDRSMSLSPPMSANTSATSAAAIYPAMGLQQAAAASAFGMLSPTQLLAANRQAAAFMAQLPMSTLANTLFPHNPAALFGAWAAQQSLPPQGTHLHSPPASPHSPLSTPLGSGKHPLNSPNSTPQHHEPAKKARKLSVKKEFQTEISMSVNDMYHTSGGPISPPSSGSSPNSTHDGAGGNAGCVGVSKDPSRDKSFTCKICSRSFGYKHVLQNHERTHTGEKPFECPECHKRFTRDHHLKTHMRLHTGEKPYHCSHCDRQFVQVANLRRHLRVHTGERPYTCEICDGKFSDSNQLKSHMLVHNGEKPFECERCHMKFRRRHHLMNHKCGIQSPPTPALSPAMSGDYPVAISAIAIEASTNRFAAMCATYGGSNESVDMEKATPEDDGPLDLSEDGASSVDGHCSNIARRKAQDIRRVFRLPPPQIPHVPSDMPEQTEPEDLSMHSPRSIGSHEQTDDIDLYDLDDAPASYMGHQQH
|
| Keyword |
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0302--Gap protein
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger
|
| Interpro |
IPR007087--Znf_C2H2
IPR015880--Znf_C2H2-like
IPR013087--Znf_C2H2/integrase_DNA-bd
|
| PROSITE |
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
|
| Pfam |
|
| Gene Ontology |
GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003705--F:transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0007411--P:axon guidance
GO:0006342--P:chromatin silencing
GO:0048749--P:compound eye development
GO:0007402--P:ganglion mother cell fate determination
GO:0061332--P:Malpighian tubule bud morphogenesis
GO:0007443--P:Malpighian tubule morphogenesis
GO:0007517--P:muscle organ development
GO:0010629--P:negative regulation of gene expression
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0007400--P:neuroblast fate determination
GO:0040034--P:regulation of development, heterochronic
GO:0035206--P:regulation of hemocyte proliferation
GO:0035290--P:trunk segmentation
GO:0007419--P:ventral cord development
GO:0035220--P:wing disc development
GO:0007354--P:zygotic determination of anterior/posterior axis, embryo
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