dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004486
Uniprot Accession P06787; CALM_YEAST; D6VQA8;
Genbank Protein ID NP_009667.1;
Genbank Nucleotide ID NM_001178457.1;
Protein Name Calmodulin
Protein Synonyms/Alias
Gene Name CMD1
Gene Synonyms/Alias YBR109C;YBR0904;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication.
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
2------MSSNLTEEQPhosphoGRID 2.021126336
27FDKDNNGSISSSELAcurated22817900
29KDNNGSISSSELATVdbPTM 3.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22817900
82RQLKSNDSEQELLEAdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 21177495; 19823750; 19779198;
102KNGDGLISAAELKHVdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988
111AELKHVLTSIGEKLTcurated22817900; 19823750; 24961812
112ELKHVLTSIGEKLTDdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17563356; 18407956; 16381945; 23193290; 21177495; 19366988;
Sequence
(Fasta)
MSSNLTEEQI AEFKEAFALF DKDNNGSISS SELATVMRSL GLSPSEAEVN DLMNEIDVDG 60
NHQIEFSEFL ALMSRQLKSN DSEQELLEAF KVFDKNGDGL ISAAELKHVL TSIGEKLTDA 120
EVDDMLREVS DGSGEINIQQ FAALLSK 148
Keyword

KW-0002--3D-structure
KW-0106--Calcium
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0903--Direct protein sequencing
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom

PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2

Pfam

PF13499--EF-hand_7

Gene Ontology

GO:0005935--C:cellular bud neck
GO:0005934--C:cellular bud tip
GO:0005823--C:central plaque of spindle pole body
GO:0000131--C:incipient cellular bud site
GO:0043332--C:mating projection tip
GO:0005509--F:calcium ion binding
GO:0048306--F:calcium-dependent protein binding
GO:0007114--P:cell budding
GO:0007010--P:cytoskeleton organization
GO:0000742--P:karyogamy involved in conjugation with cellular fusion
GO:0016237--P:lysosomal microautophagy
GO:0006607--P:NLS-bearing protein import into nucleus
GO:0006661--P:phosphatidylinositol biosynthetic process
GO:0006898--P:receptor-mediated endocytosis
GO:0051300--P:spindle pole body organization
GO:0042991--P:transcription factor import into nucleus
GO:0042144--P:vacuole fusion, non-autophagic