dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004484
Uniprot Accession P06784; STE7_YEAST; D6VRJ2;
Genbank Protein ID NP_010122.1;
Genbank Nucleotide ID NM_001180219.1;
Protein Name Serine/threonine-protein kinase STE7
Protein Synonyms/Alias
Gene Name STE7
Gene Synonyms/Alias YDL159W;D1525;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast. It is thought that it is phosphorylated by the ste11 protein kinase and that it can phosphorylate the FUS3 and or KSS1 kinases.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
149QGLSNIATPVENEHSdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
359VSKKLINSIADTFVGdbPTM 3.0;Phospho.ELM 9.0;PhosphoGRID 2.0;UniProt8131746; 16381945; 23193290
363LINSIADTFVGTSTYdbPTM 3.0;Phospho.ELM 9.0;PhosphoGRID 2.0;UniProt8131746; 16381945; 23193290; 8159759
471DLIMKYVSPSKDDKFPhosphoGRID 2.0;curated19779198; 22817900
Sequence
(Fasta)
MFQRKTLQRR NLKGLNLNLH PDVGNNGQLQ EKTETHQGQS RIEGHVMSNI NAIQNNSNLF 60
LRRGIKKKLT LDAFGDDQAI SKPNTVVIQQ PQNEPVLVLS SLSQSPCVSS SSSLSTPCII 120
DAYSNNFGLS PSSTNSTPST IQGLSNIATP VENEHSISLP PLEESLSPAA ADLKDTLSGT 180
SNGNYIQLQD LVQLGKIGAG NSGTVVKALH VPDSKIVAKK TIPVEQNNST IINQLVRELS 240
IVKNVKPHEN IITFYGAYYN QHINNEIIIL MEYSDCGSLD KILSVYKRFV QRGTVSSKKT 300
WFNELTISKI AYGVLNGLDH LYRQYKIIHR DIKPSNVLIN SKGQIKLCDF GVSKKLINSI 360
ADTFVGTSTY MSPERIQGNV YSIKGDVWSL GLMIIELVTG EFPLGGHNDT PDGILDLLQR 420
IVNEPSPRLP KDRIYSKEMT DFVNRCCIKN ERERSSIHEL LHHDLIMKYV SPSKDDKFRH 480
WCRKIKSKIK EDKRIKREAL DRAKLEKKQS ERSTH 516
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0589--Pheromone response
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

Gene Ontology

GO:0005737--C:cytoplasm
GO:0043332--C:mating projection tip
GO:0005524--F:ATP binding
GO:0004708--F:MAP kinase kinase activity
GO:0004674--F:protein serine/threonine kinase activity
GO:0071508--P:activation of MAPK activity involved in conjugation with cellular fusion
GO:0001403--P:invasive growth in response to glucose limitation
GO:0000196--P:MAPK cascade involved in cell wall organization or biogenesis
GO:0071507--P:MAPK cascade involved in conjugation with cellular fusion
GO:0006468--P:protein phosphorylation
GO:0007124--P:pseudohyphal growth
GO:0042981--P:regulation of apoptotic process
GO:0007346--P:regulation of mitotic cell cycle
GO:0010525--P:regulation of transposition, RNA-mediated
GO:0001402--P:signal transduction involved in filamentous growth
GO:0031098--P:stress-activated protein kinase signaling cascade