dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004483
Uniprot Accession P06783; STE3_YEAST; D6VX23;
Genbank Protein ID NP_012743.1;
Genbank Nucleotide ID NM_001179744.1;
Protein Name Pheromone a factor receptor
Protein Synonyms/Alias
Gene Name STE3
Gene Synonyms/Alias YKL178C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Receptor for the peptide pheromone a factor.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
418QSFDDEISLGGFSKVcurated24961812
430SKVTLDYSEKLHNSAdbPTM 3.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19060867; 19366988; 24961812;
436YSEKLHNSASSNFEGcurated22817900; 20377248
438EKLHNSASSNFEGEScurated20377248
439KLHNSASSNFEGESLcurated22817900; 20377248; 19547744
445SSNFEGESLCYSPAScurated22817900; 20377248
452SLCYSPASKEENSSScurated22817900; 25315811; 20377248
458ASKEENSSSNEHSSEcurated25315811
464SSSNEHSSENTAGP-curated25315811
Sequence
(Fasta)		MSYKSAIIGL CLLAVILLAP PLAWHSHTKN IPAIILITWL LTMNLTCIVD AAIWSDDDFL 60
TRWDGKGWCD IVIKLQVGAN IGISCAVTNI IYNLHTILKA DSVLPDLSSW TKIVKDLVIS 120
LFTPVMVMGF SYLLQVFRYG IARYNGCQNL LSPTWITTVL YTMWMLIWSF VGAVYATLVL 180
FVFYKKRKDV RDILHCTNSG LNLTRFARLL IFCFIIILVM FPFSVYTFVQ DLQQVEGHYT 240
FKNTHSSTIW NTIIKFDPGR PIYNIWLYVL MSYLVFLIFG LGSDALHMYS KFLRSIKLGF 300
VLDMWKRFID KNKEKRVGIL LNKLSSRKES RNPFSTDSEN YISTCTENYS PCVGTPISQA 360
HFYVDYRIPD DPRKSQNKSK KYLFADKETD DILDEIDLKE SRHIPYVTQG QSFDDEISLG 420
GFSKVTLDYS EKLHNSASSN FEGESLCYSP ASKEENSSSN EHSSENTAGP 471
Keyword

KW-0181--Complete proteome
KW-0297--G-protein coupled receptor
KW-0472--Membrane
KW-0589--Pheromone response
KW-0675--Receptor
KW-1185--Reference proteome
KW-0807--Transducer
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR001499--GPCR_STE3
PROSITE
Pfam

PF02076--STE3
Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004933--F:mating-type a-factor pheromone receptor activity
GO:0000755--P:cytogamy
GO:0000750--P:pheromone-dependent signal transduction involved in conjugation with cellular fusion