dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004480
Uniprot Accession P06779; RAD7_YEAST; D6VWM3;
Genbank Protein ID NP_012586.1;
Genbank Nucleotide ID NM_001181710.1;
Protein Name DNA repair protein RAD7
Protein Synonyms/Alias
Gene Name RAD7
Gene Synonyms/Alias YJR052W;J1665;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Component of the global genome repair (GGR) complex which promotes global genome nucleotide excision repair (GG-NER) which removes DNA damage from nontranscribing DNA. This protein is one of 10 proteins (RAD1, 2,3,4,7,10,14, 16,23 and MMS19) involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.
Phosphorylation Sites
dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
64KGKAEDDSFTAEISRdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 19366988; 26040289;
83EEIDEIGTGSGTETEPhosphoGRID 2.0;curated21126336; 19779198; 22369663; 25315811
85IDEIGTGSGTETERAdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 21081558; 19060867;
87EIGTGSGTETERAQVPhosphoGRID 2.0;PhosphoPep 2.0;curated19779198; 19060867; 22817900; 25315811
96TERAQVSYDARMKLVdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
107MKLVPADSDEEEYETdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;curated17563356; 16381945; 23193290; 19779198; 19060867; 26040406;
115DEEEYETSHISDTPVPhosphoPep 2.019060867
118EYETSHISDTPVSLSPhosphoGRID 2.0;PhosphoPep 2.0;curated19779198; 19060867; 24961812; 25315811; 20377248
Sequence
(Fasta)
MYRSRNRPKR GGENEVKGPN SALTQFLREE GISAENIKQK WYQRQSKKQE DATDEKKGKA 60
EDDSFTAEIS RVVEDEEIDE IGTGSGTETE RAQVSYDARM KLVPADSDEE EYETSHISDT 120
PVSLSSANDR ESLTKKRQNT AKIIQNRRRK RKRAADLLDR RVNKVSSLQS LCITKISENI 180
SKWQKEADES SKLVFNKLRD VLGGVSTANL NNLAKALSKN RALNDHTLQL FLKTDLKRLT 240
FSDCSKISFD GYKTLAIFSP HLTELSLQMC GQLNHESLLY IAEKLPNLKS LNLDGPFLIN 300
EDTWEKFFVI MKGRLEEFHI SNTHRFTDKS LSNLLINCGS TLVSLGLSRL DSISNYALLP 360
QYLVNDEFHS LCIEYPFNEE DVNDEIIINL LGQIGRTLRK LVLNGCIDLT DSMIINGLTA 420
FIPEKCPLEV LSLEESDQIT TDSLSYFFSK VELNNLIECS FRRCLQLGDM AIIELLLNGA 480
RDSLRSLNLN SLKELTKEAF VALACPNLTY LDLGFVRCVD DSVIQMLGEQ NPNLTVIDVF 540
GDNLVTEKAT MRPGLTLIGR QSDSI 566
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro
PROSITE
Pfam
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0000113--C:nucleotide-excision repair factor 4 complex
GO:0000715--P:nucleotide-excision repair, DNA damage recognition
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process