dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004479
Uniprot Accession P06778; RAD52_YEAST; D6VZE2;
Genbank Protein ID NP_013680.2;
Genbank Nucleotide ID NM_001182390.1;
Protein Name DNA repair and recombination protein RAD52
Protein Synonyms/Alias
Gene Name RAD52
Gene Synonyms/Alias YML032C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Involved in DNA double-strand break (DSB) repair and recombination. Promotes the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.
Phosphorylation Sites
dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
214VTNTNPDSTKNLVKIcurated25315811
229ENTVSRGTPMMAAPAcurated25315811
302DPVVAKQSPTASSNPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19823750; 19795423; 19366988;
304VVAKQSPTASSNPEAdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22817900; 25521595;
306AKQSPTASSNPEAEQdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
307KQSPTASSNPEAEQIdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22817900
349QAQSIRHTVDQTTSKPhosphoGRID 2.019779198
361TSKHIPASVLKDKTMPhosphoGRID 2.019779198
411GNQVPRETTPIKTNAcurated20377248
412NQVPRETTPIKTNATcurated22817900; 24961812; 20377248
Sequence
(Fasta)
MNEIMDMDEK KPVFGNHSED IQTKLDKKLG PEYISKRVGF GTSRIAYIEG WRVINLANQI 60
FGYNGWSTEV KSVVIDFLDE RQGKFSIGCT AIVRVTLTSG TYREDIGYGT VENERRKPAA 120
FERAKKSAVT DALKRSLRGF GNALGNCLYD KDFLAKIDKV KFDPPDFDEN NLFRPTDEIS 180
ESSRTNTLHE NQEQQQYPNK RRQLTKVTNT NPDSTKNLVK IENTVSRGTP MMAAPAEANS 240
KNSSNKDTDL KSLDASKQDQ DDLLDDSLMF SDDFQDDDLI NMGNTNSNVL TTEKDPVVAK 300
QSPTASSNPE AEQITFVTAK AATSVQNERY IGEESIFDPK YQAQSIRHTV DQTTSKHIPA 360
SVLKDKTMTT ARDSVYEKFA PKGKQLSMKN NDKELGPHML EGAGNQVPRE TTPIKTNATA 420
FPPAAAPRFA PPSKVVHPNG NGAVPAVPQQ RSTRREVGRP KINPLHARKP T 472
Keyword

KW-0024--Alternative initiation
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0233--DNA recombination
KW-0234--DNA repair
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR004585--DNA_recomb/repair_Rad52
IPR007232--Rad52_Rad59_Rad22

PROSITE
Pfam

PF04098--Rad52_Rad22

Gene Ontology

GO:0000228--C:nuclear chromosome
GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0000150--F:recombinase activity
GO:0006277--P:DNA amplification
GO:0000730--P:DNA recombinase assembly
GO:0000733--P:DNA strand renaturation
GO:0000727--P:double-strand break repair via break-induced replication
GO:0000724--P:double-strand break repair via homologous recombination
GO:0045002--P:double-strand break repair via single-strand annealing
GO:0000709--P:meiotic joint molecule formation
GO:0006301--P:postreplication repair
GO:0000722--P:telomere maintenance via recombination