dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004478
Uniprot Accession P06777; RAD1_YEAST; D6W3Z0;
Genbank Protein ID NP_015303.1;
Genbank Nucleotide ID NM_001183836.1;
Protein Name DNA repair protein RAD1
Protein Synonyms/Alias
Gene Name RAD1
Gene Synonyms/Alias YPL022W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Along with RAD10 forms an endonuclease that specifically degrades single-stranded DNA.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
10QLFYQGDSDDELQEEcurated22817900; 19547744
40NEDEPDDSNHLNEVEPhosphoGRID 2.0;curated20489023; 19779198; 26040289; 22817900; 24961812
51NEVENEDSKVLDDDAcurated24961812
181DDDTAVESDDELFERPhosphoGRID 2.020489023
592EKLRNAGTNVDMEVVcurated22817900; 19547744
613SEEIKKGSGDDLDDGPhosphoGRID 2.0;UniProt;curated20489023; 21126336; 19779198; 22817900; 24961812; 25315811
1071KEEQEQESTDENLESdbPTM 3.0;PhosphoGRID 2.0;UniProt;curated17563356; 16381945; 23193290; 21126336; 19779198; 26040289;
1072EEQEQESTDENLESPdbPTM 3.0;PhosphoGRID 2.0;UniProt;curated17563356; 16381945; 23193290; 19779198; 26040289; 22817900;
1078STDENLESPGKTTDDcurated25315811
Sequence
(Fasta)		MSQLFYQGDS DDELQEELTR QTTQASQSSK IKNEDEPDDS NHLNEVENED SKVLDDDAVL 60
YPLIPNEPDD IETSKPNIND IRPVDIQLTL PLPFQQKVVE NSLITEDALI IMGKGLGLLD 120
IVANLLHVLA TPTSINGQLK RALVLVLNAK PIDNVRIKEA LEELSWFSNT GKDDDDTAVE 180
SDDELFERPF NVVTADSLSI EKRRKLYISG GILSITSRIL IVDLLSGIVH PNRVTGMLVL 240
NADSLRHNSN ESFILEIYRS KNTWGFIKAF SEAPETFVME FSPLRTKMKE LRLKNVLLWP 300
RFRVEVSSCL NATNKTSHNK VIEVKVSLTN SMSQIQFGLM ECLKKCIAEL SRKNPELALD 360
WWNMENVLDI NFIRSIDSVM VPNWHRISYE SKQLVKDIRF LRHLLKMLVT SDAVDFFGEI 420
QLSLDANKPS VSRKYSESPW LLVDEAQLVI SYAKKRIFYK NEYTLEENPK WEQLIHILHD 480
ISHERMTNHL QGPTLVACSD NLTCLELAKV LNASNKKRGV RQVLLNKLKW YRKQREETKK 540
LVKEVQSQDT FPENATLNVS STFSKEQVTT KRRRTRGASQ VAAVEKLRNA GTNVDMEVVF 600
EDHKLSEEIK KGSGDDLDDG QEENAANDSK IFEIQEQENE ILIDDGDAEF DNGELEYVGD 660
LPQHITTHFN KDLWAEHCNE YEYVDRQDEI LISTFKSLND NCSLQEMMPS YIIMFEPDIS 720
FIRQIEVYKA IVKDLQPKVY FMYYGESIEE QSHLTAIKRE KDAFTKLIRE NANLSHHFET 780
NEDLSHYKNL AERKLKLSKL RKSNTRNAGG QQGFHNLTQD VVIVDTREFN ASLPGLLYRY 840
GIRVIPCMLT VGDYVITPDI CLERKSISDL IGSLQNNRLA NQCKKMLKYY AYPTLLIEFD 900
EGQSFSLEPF SERRNYKNKD ISTVHPISSK LSQDEIQLKL AKLVLRFPTL KIIWSSSPLQ 960
TVNIILELKL GREQPDPSNA VILGTNKVRS DFNSTAKGLK DGDNESKFKR LLNVPGVSKI 1020
DYFNLRKKIK SFNKLQKLSW NEINELINDE DLTDRIYYFL RTEKEEQEQE STDENLESPG 1080
KTTDDNALHD HHNDVPEAPV 1101
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0255--Endonuclease
KW-0378--Hydrolase
KW-0540--Nuclease
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR020819--DNA_repair_nuc_XPF/helicase
IPR006166--ERCC4_domain
IPR006167--Rad1
IPR011335--Restrct_endonuc-II-like
IPR010994--RuvA_2-like
PROSITE
Pfam

PF02732--ERCC4
Gene Ontology

GO:0000110--C:nucleotide-excision repair factor 1 complex
GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0004519--F:endonuclease activity
GO:0003697--F:single-stranded DNA binding
GO:0006277--P:DNA amplification
GO:0000724--P:double-strand break repair via homologous recombination
GO:0000736--P:double-strand break repair via single-strand annealing, removal of nonhomologous ends
GO:0000710--P:meiotic mismatch repair
GO:0006312--P:mitotic recombination
GO:1901255--P:nucleotide-excision repair involved in interstrand cross-link repair
GO:0006296--P:nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0000735--P:removal of nonhomologous ends
GO:0000712--P:resolution of meiotic recombination intermediates