dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004477
Uniprot Accession P06775; HIP1_YEAST; D6VUX3;
Genbank Protein ID NP_011707.1;
Genbank Nucleotide ID NM_001181320.1;
Protein Name Histidine permease
Protein Synonyms/Alias
Gene Name HIP1
Gene Synonyms/Alias YGR191W;G7572;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 High-affinity permease for histidine.
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
50TDSAFPLSSKDSPGIPhosphoPep 2.019060867
51DSAFPLSSKDSPGINPhosphoPep 2.019060867
54FPLSSKDSPGINQTTdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17330950; 16381945; 23193290; 19779198; 19060867; 19366988;
66QTTNDITSSDRFRRNPhosphoPep 2.0;curated19060867; 26040289; 25315811
67TTNDITSSDRFRRNEPhosphoPep 2.0;curated19060867; 26040289; 22817900; 25315811
76RFRRNEDTEQEDINNPhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated19779198; 19060867; 26040289; 22817900; 25882841; 25315811
576GRKQVDLTLRREEMRdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.015665377; 16381945; 23193290; 19366988
Sequence
(Fasta)		MPRNPLKKEY WADVVDGFKP ATSPAFENEK ESTTFVTELT SKTDSAFPLS SKDSPGINQT 60
TNDITSSDRF RRNEDTEQED INNTNLSKDL SVRHLLTLAV GGAIGTGLYV NTGAALSTGG 120
PASLVIDWVI ISTCLFTVIN SLGELSAAFP VVGGFNVYSM RFIEPSFAFA VNLNYLAQWL 180
VLLPLELVAA SITIKYWNDK INSDAWVAIF YATIALANML DVKSFGETEF VLSMIKILSI 240
IGFTILGIVL SCGGGPHGGY IGGKYWHDPG AFVGHSSGTQ FKGLCSVFVT AAFSYSGIEM 300
TAVSAAESKN PRETIPKAAK RTFWLITASY VTILTLIGCL VPSNDPRLLN GSSSVDAASS 360
PLVIAIENGG IKGLPSLMNA IILIAVVSVA NSAVYACSRC MVAMAHIGNL PKFLNRVDKR 420
GRPMNAILLT LFFGLLSFVA ASDKQAEVFT WLSALSGLST IFCWMAINLS HIRFRQAMKV 480
QERSLDELPF ISQTGVKGSW YGFIVLFLVL IASFWTSLFP LGGSGASAES FFEGYLSFPI 540
LIVCYVGHKL YTRNWTLMVK LEDMDLDTGR KQVDLTLRRE EMRIERETLA KRSFVTRFLH 600
FWC 604
Keyword

KW-0029--Amino-acid transport
KW-0181--Complete proteome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR004841--AA-permease/SLC12A_dom
IPR002293--AA/rel_permease1
IPR004762--Amino_acid_permease_fungi
IPR004840--Amoino_acid_permease_CS
PROSITE

PS00218--AMINO_ACID_PERMEASE_1
Pfam

PF00324--AA_permease
Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0005886--C:plasma membrane
GO:0005773--C:vacuole
GO:0015297--F:antiporter activity
GO:0005291--F:high-affinity L-histidine transmembrane transporter activity
GO:0003333--P:amino acid transmembrane transport
GO:0015817--P:histidine transport
GO:0089709--P:L-histidine transmembrane transport
GO:0006828--P:manganese ion transport