dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004464
Uniprot Accession P06738; PHSG_YEAST; D6W4G1;
Genbank Protein ID NP_015486.1;
Genbank Nucleotide ID NM_001184257.1;
Protein Name Glycogen phosphorylase
Protein Synonyms/Alias
Gene Name GPH1
Gene Synonyms/Alias YPR160W;P9584.1;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Phosphorylation Sites
 dbPAF PTMs: 16
PositionPeptidesSourceReferences ( PMIDs )
5---MPPASTSTTNDMcurated19823750
9PPASTSTTNDMITEEPhosphoGRID 2.07592925
14STTNDMITEEPTSPHcurated22817900; 23607784
18DMITEEPTSPHQIPRdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 20702584; 15665377; 21081558;
19MITEEPTSPHQIPRLdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 20702584; 21081558; 19060867;
27PHQIPRLTRRLTGFLPhosphoGRID 2.07592925
31PRLTRRLTGFLPQEIdbPTM 3.0;Phospho.ELM 9.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated1092346; 1613787; 17330950; 17563356; 18407956; 16381945; 23
43QEIKSIDTMIPLKSRPhosphoGRID 2.0;curated19779198; 25315811
82VETTLARSLYNCDDMcurated22817900; 19547744
308RLWQARPTTEFDFAKcurated22369663
324NNGDYKNSVAQQQRAcurated25315811
333AQQQRAESITAVLYPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 19366988; 22817900;
335QQRAESITAVLYPNDPhosphoGRID 2.0;curated19779198; 22817900
551WLKQANPSLAKLISEcurated25315811
580KLTQLGKYVEDKEFLPhosphoGRID 2.021126336
722FVADYNVSKAEIIIPcurated22817900; 19547744
Sequence
(Fasta)		MPPASTSTTN DMITEEPTSP HQIPRLTRRL TGFLPQEIKS IDTMIPLKSR ALWNKHQVKK 60
FNKAEDFQDR FIDHVETTLA RSLYNCDDMA AYEAASMSIR DNLVIDWNKT QQKFTTRDPK 120
RVYYLSLEFL MGRALDNALI NMKIEDPEDP AASKGKPREM IKGALDDLGF KLEDVLDQEP 180
DAGLGNGGLG RLAACFVDSM ATEGIPAWGY GLRYEYGIFA QKIIDGYQVE TPDYWLNSGN 240
PWEIERNEVQ IPVTFYGYVD RPEGGKTTLS ASQWIGGERV LAVAYDFPVP GFKTSNVNNL 300
RLWQARPTTE FDFAKFNNGD YKNSVAQQQR AESITAVLYP NDNFAQGKEL RLKQQYFWCA 360
ASLHDILRRF KKSKRPWTEF PDQVAIQLND THPTLAIVEL QRVLVDLEKL DWHEAWDIVT 420
KTFAYTNHTV MQEALEKWPV GLFGHLLPRH LEIIYDINWF FLQDVAKKFP KDVDLLSRIS 480
IIEENSPERQ IRMAFLAIVG SHKVNGVAEL HSELIKTTIF KDFVKFYGPS KFVNVTNGIT 540
PRRWLKQANP SLAKLISETL NDPTEEYLLD MAKLTQLGKY VEDKEFLKKW NQVKLNNKIR 600
LVDLIKKEND GVDIINREYL DDTLFDMQVK RIHEYKRQQL NVFGIIYRYL AMKNMLKNGA 660
SIEEVAKKYP RKVSIFGGKS APGYYMAKLI IKLINCVADI VNNDESIEHL LKVVFVADYN 720
VSKAEIIIPA SDLSEHISTA GTEASGTSNM KFVMNGGLII GTVDGANVEI TREIGEDNVF 780
LFGNLSENVE ELRYNHQYHP QDLPSSLDSV LSYIESGQFS PENPNEFKPL VDSIKYHGDY 840
YLVSDDFESY LATHELVDQE FHNQRSEWLK KSVLSVANVG FFSSDRCIEE YSDTIWNVEP 900
VT 903
Keyword

KW-0002--3D-structure
KW-0119--Carbohydrate metabolism
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0321--Glycogen metabolism
KW-0328--Glycosyltransferase
KW-0597--Phosphoprotein
KW-0663--Pyridoxal phosphate
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR011833--Glycg_phsphrylas
IPR000811--Glyco_trans_35
PROSITE

PS00102--PHOSPHORYLASE
Pfam

PF00343--Phosphorylase
Gene Ontology

GO:0005737--C:cytoplasm
GO:0008184--F:glycogen phosphorylase activity
GO:0030170--F:pyridoxal phosphate binding
GO:0005980--P:glycogen catabolic process