dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004455
Uniprot Accession P06704; CDC31_YEAST; D6W2V8;
Genbank Protein ID NP_014900.3;
Genbank Nucleotide ID NM_001183676.3;
Protein Name Cell division control protein 31
Protein Synonyms/Alias Nuclear pore protein CDC31;Nucleoporin CDC31;
Gene Name CDC31
Gene Synonyms/Alias DSK1;YOR257W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Functions as a component of the nuclear pore complex (NPC) and the spindle pole body (SPB) half-bridge. At the SPB, it is recruited by KAR1 and MPS3 to the SPB half-bridge and involved in the initial steps of SPB duplication. It probably plays a similar role in de novo assembly of NPCs at the nuclear envelope. Also involved in connection with the protein kinase KIC1 in the maintenance of cell morphology and integrity.
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
6--MSKNRSSLQSGPLPhosphoGRID 2.0;curated20489023; 19823750
7-MSKNRSSLQSGPLNPhosphoGRID 2.020489023
10KNRSSLQSGPLNSELPhosphoGRID 2.0;curated19823750; 19795423
110QLFDDDHTGKISIKNPhosphoGRID 2.020489023
128VAKELGETLTDEELRPhosphoGRID 2.020489023; 21126336
130KELGETLTDEELRAMdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 20489023; 21081558; 19366988;
Sequence
(Fasta)		MSKNRSSLQS GPLNSELLEE QKQEIYEAFS LFDMNNDGFL DYHELKVAMK ALGFELPKRE 60
ILDLIDEYDS EGRHLMKYDD FYIVMGEKIL KRDPLDEIKR AFQLFDDDHT GKISIKNLRR 120
VAKELGETLT DEELRAMIEE FDLDGDGEIN ENEFIAICTD S 162
Keyword

KW-0002--3D-structure
KW-0106--Calcium
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0479--Metal-binding
KW-0498--Mitosis
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
Pfam

PF13499--EF-hand_7
Gene Ontology

GO:0005825--C:half bridge of spindle pole body
GO:0005643--C:nuclear pore
GO:0070390--C:transcription export complex 2
GO:0005509--F:calcium ion binding
GO:0042802--F:identical protein binding
GO:0005200--F:structural constituent of cytoskeleton
GO:0051301--P:cell division
GO:0007020--P:microtubule nucleation
GO:0007067--P:mitotic nuclear division
GO:0051028--P:mRNA transport
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0015031--P:protein transport
GO:0043549--P:regulation of kinase activity
GO:0030474--P:spindle pole body duplication