Tag |
Content |
dbPAF ID |
dbPAF-0004442 |
Uniprot Accession |
P06606; TBA4_DROME; Q9VT30; |
Genbank Protein ID |
NP_524009.2; |
Genbank Nucleotide ID |
NM_079285.4; |
Protein Name |
Tubulin alpha-4 chain |
Protein Synonyms/Alias |
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Gene Name |
alphaTub67C |
Gene Synonyms/Alias |
TubA67C;CG8308; |
Organism |
Drosophila melanogaster(Fruit fly) |
NCBI Taxa ID |
7227 |
Functional Description (View all) |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.Functional Description
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
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Phosphorylation Sites
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dbPAF PTMs: 2 |
Sequence (Fasta) | MREVVSIQIG QCGIQIGNAC WELYLLEHGI NLDGSLKTKE ELTASGSSAS VGHDTSANDA 60 RTFFTETGNG KQVPRSIFVD LEPTVIDDVR NGCMRELYHP EQLISGKEDA ANNYARGRYS 120 IGKEVIDRVT SRLQKIAEQC DSLQGFLIFH SLGGGTGSGF TSLLVERLST DYSKKCKLDF 180 AVYPSPKVST AVVEPYNALL TTHSTMDHSD CVFMVDNEAI YDICNNSLGV DRPAYRNLNR 240 LIAQIVSSTT ASLRFSGSMN VDLNEFQTNL VPFPRIHFPL VAYAPLMSAE RSAHEQHAIT 300 TLTNACFESS NMMVKCDPRA GKFMACCMLY RGDVVPKDVN AAVSAIKSKR HIQFVDWCPT 360 GFKIGINYEK PAFVPDGDLA KTSRACCMLS NTTAISVAFS NLSYKFDLMF KKRAFVHWYV 420 GEGMEEGEFT EARENIAVLE RDFEEVGLDN AEEGGDEDFD EF
463Fasta Sequence
>P06606|alphaTub67C|Drosophila melanogaster(Fruit fly) MREVVSIQIGQCGIQIGNACWELYLLEHGINLDGSLKTKEELTASGSSASVGHDTSANDARTFFTETGNGKQVPRSIFVDLEPTVIDDVRNGCMRELYHPEQLISGKEDAANNYARGRYSIGKEVIDRVTSRLQKIAEQCDSLQGFLIFHSLGGGTGSGFTSLLVERLSTDYSKKCKLDFAVYPSPKVSTAVVEPYNALLTTHSTMDHSDCVFMVDNEAIYDICNNSLGVDRPAYRNLNRLIAQIVSSTTASLRFSGSMNVDLNEFQTNLVPFPRIHFPLVAYAPLMSAERSAHEQHAITTLTNACFESSNMMVKCDPRAGKFMACCMLYRGDVVPKDVNAAVSAIKSKRHIQFVDWCPTGFKIGINYEKPAFVPDGDLAKTSRACCMLSNTTAISVAFSNLSYKFDLMFKKRAFVHWYVGEGMEEGEFTEARENIAVLERDFEEVGLDNAEEGGDEDFDEF
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Keyword |
KW-0181--Complete proteome KW-0963--Cytoplasm KW-0206--Cytoskeleton KW-0342--GTP-binding KW-0493--Microtubule KW-0547--Nucleotide-binding KW-1185--Reference proteome
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Interpro |
IPR002452--Alpha_tubulin IPR008280--Tub_FtsZ_C IPR000217--Tubulin IPR018316--Tubulin/FtsZ_2-layer-sand-dom IPR023123--Tubulin_C IPR017975--Tubulin_CS IPR003008--Tubulin_FtsZ_GTPase
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PROSITE |
PS00227--TUBULIN
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Pfam |
PF00091--Tubulin PF03953--Tubulin_C
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Gene Ontology |
GO:0055028--C:cortical microtubule GO:0005737--C:cytoplasm GO:0005874--C:microtubule GO:0005634--C:nucleus GO:0048471--C:perinuclear region of cytoplasm GO:0005886--C:plasma membrane GO:0005525--F:GTP binding GO:0003924--F:GTPase activity GO:0005200--F:structural constituent of cytoskeleton GO:0007417--P:central nervous system development GO:0051298--P:centrosome duplication GO:0009792--P:embryo development ending in birth or egg hatching GO:0040016--P:embryonic cleavage GO:0035038--P:female pronucleus assembly GO:0007017--P:microtubule-based process GO:0007052--P:mitotic spindle organization GO:0051028--P:mRNA transport GO:0022008--P:neurogenesis GO:0000280--P:nuclear division GO:0007422--P:peripheral nervous system development GO:0035046--P:pronuclear migration GO:0051258--P:protein polymerization GO:0035044--P:sperm aster formation
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