dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004441
Uniprot Accession P06604; TBA2_DROME; B5RJ60; Q8MYS4; Q9VH86;
Genbank Protein ID NP_524297.1;
Genbank Nucleotide ID NM_079573.5;
Protein Name Tubulin alpha-2 chain
Protein Synonyms/Alias
Gene Name alphaTub85E
Gene Synonyms/Alias TUBA85E;CG9476;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
439YEEVGIDSTTELGEDcurated22817900
440EEVGIDSTTELGEDEcurated22817900
441EVGIDSTTELGEDEEcurated22817900
Sequence
(Fasta)		MRECISVHIG QAGVQIGNAC WELYCLEHGI QPDGHMPSDK TVGGGDDSFS TFFSETGAGK 60
HVPRAVFVDL EPTVVDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIVDVVLD 120
RIRKLADQCT GLQGFLVFHS FGGGTGSGFT SLLMERLSVD YGKKSKLEFS IYPAPQVSTA 180
VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYMNLNRL IGQIVSSITA 240
SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISVEK AYHEQLTVAE ITNACFEPAN 300
QMVKCDPRRG KYMACCMLYR GDVVPKDVNA AIATIKTKRS IQFVDWCPTG FKVGINYQPP 360
TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFAE 420
AREDLAALEK DYEEVGIDST TELGEDEEY
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0903--Direct protein sequencing
KW-0342--GTP-binding
KW-0493--Microtubule
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
Interpro

IPR002452--Alpha_tubulin
IPR008280--Tub_FtsZ_C
IPR000217--Tubulin
IPR018316--Tubulin/FtsZ_2-layer-sand-dom
IPR023123--Tubulin_C
IPR017975--Tubulin_CS
IPR003008--Tubulin_FtsZ_GTPase
PROSITE

PS00227--TUBULIN
Pfam

PF00091--Tubulin
PF03953--Tubulin_C
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0005200--F:structural constituent of cytoskeleton
GO:0051298--P:centrosome duplication
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0007052--P:mitotic spindle organization
GO:0051258--P:protein polymerization