| Tag |
Content |
| dbPAF ID |
dbPAF-0004440 |
| Uniprot Accession |
P06603; TBA1_DROME; Q9VI59;
|
| Genbank Protein ID |
NP_476772.1;
|
| Genbank Nucleotide ID |
NM_057424.4;
|
| Protein Name |
Tubulin alpha-1 chain |
| Protein Synonyms/Alias |
|
| Gene Name |
alphaTub84B |
| Gene Synonyms/Alias |
tubA84B;CG1913; |
| Organism |
Drosophila melanogaster(Fruit fly) |
| NCBI Taxa ID |
7227 |
Functional Description
(View all) |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.Functional Description
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TVGGGDDSFN TFFSETGAGK 60
HVPRAVFVDL EPTVVDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIVDLVLD 120
RIRKLADQCT GLQGFLIFHS FGGGTGSGFT SLLMERLSVD YGKKSKLEFA IYPAPQVSTA 180
VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL IGQIVSSITA 240
SLRFDGALNV DLTEFQTNLV PYPRIHFPLV TYAPVISAEK AYHEQLSVAE ITNACFEPAN 300
QMVKCDPRHG KYMACCMLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYQPP 360
TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE 420
AREDLAALEK DYEEVGMDSG DGEGEGAEEY
451Fasta Sequence
>P06603|alphaTub84B|Drosophila melanogaster(Fruit fly)
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEGEGAEEY
|
| Keyword |
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0342--GTP-binding
KW-0493--Microtubule
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
|
| Interpro |
IPR002452--Alpha_tubulin
IPR008280--Tub_FtsZ_C
IPR000217--Tubulin
IPR018316--Tubulin/FtsZ_2-layer-sand-dom
IPR023123--Tubulin_C
IPR017975--Tubulin_CS
IPR003008--Tubulin_FtsZ_GTPase
|
| PROSITE |
PS00227--TUBULIN
|
| Pfam |
PF00091--Tubulin
PF03953--Tubulin_C
|
| Gene Ontology |
GO:0000235--C:astral microtubule
GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0005819--C:spindle
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0005200--F:structural constituent of cytoskeleton
GO:0019730--P:antimicrobial humoral response
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0007052--P:mitotic spindle organization
GO:0051258--P:protein polymerization
|
