dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004418
Uniprot Accession P06244; KAPA_YEAST; D6VW23; P11595; Q2VQW1;
Genbank Protein ID NP_012371.2;
Genbank Nucleotide ID NM_001181597.2;
Protein Name cAMP-dependent protein kinase type 1
Protein Synonyms/Alias
Gene Name TPK1
Gene Synonyms/Alias PKA1;SRA3;YJL164C;J0541;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
13QNGGGQKSLDDRQGEPhosphoGRID 2.0;PhosphoPep 2.0;curated19823750; 19779198; 19795423; 19060867; 26040406; 22369663;
22DDRQGEESQKGETSEcurated24961812; 20377248
28ESQKGETSERETTATcurated25315811
32GETSERETTATESGNcurated25315811
35SERETTATESGNESKcurated25521595; 24961812; 25315811
37RETTATESGNESKSVcurated19823750; 25521595; 24961812; 25315811
41ATESGNESKSVEKEGcurated24961812; 25315811
43ESGNESKSVEKEGGEPhosphoPep 2.0;curated19060867; 24961812
239AKYVPDVTYTLCGTPdbPTM 3.018407956; 16381945; 23193290
240KYVPDVTYTLCGTPDdbPTM 3.018407956; 16381945; 23193290
241YVPDVTYTLCGTPDYdbPTM 3.015665377; 17563356; 18407956; 16381945; 23193290
Sequence
(Fasta)		MSTEEQNGGG QKSLDDRQGE ESQKGETSER ETTATESGNE SKSVEKEGGE TQEKPKQPHV 60
TYYNEEQYKQ FIAQARVTSG KYSLQDFQIL RTLGTGSFGR VHLIRSRHNG RYYAMKVLKK 120
EIVVRLKQVE HTNDERLMLS IVTHPFIIRM WGTFQDAQQI FMIMDYIEGG ELFSLLRKSQ 180
RFPNPVAKFY AAEVCLALEY LHSKDIIYRD LKPENILLDK NGHIKITDFG FAKYVPDVTY 240
TLCGTPDYIA PEVVSTKPYN KSIDWWSFGI LIYEMLAGYT PFYDSNTMKT YEKILNAELR 300
FPPFFNEDVK DLLSRLITRD LSQRLGNLQN GTEDVKNHPW FKEVVWEKLL SRNIETPYEP 360
PIQQGQGDTS QFDKYPEEDI NYGVQGEDPY ADLFRDF 398
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0067--ATP-binding
KW-0114--cAMP
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF00069--Pkinase
Gene Ontology

GO:0005952--C:cAMP-dependent protein kinase complex
GO:0005737--C:cytoplasm
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004691--F:cAMP-dependent protein kinase activity
GO:0007049--P:cell cycle
GO:0051301--P:cell division
GO:0010737--P:protein kinase A signaling
GO:0006468--P:protein phosphorylation
GO:0007265--P:Ras protein signal transduction
GO:0016241--P:regulation of macroautophagy