| Tag |
Content |
| dbPAF ID |
dbPAF-0004417 |
| Uniprot Accession |
P06243; CDC7_YEAST; D6VRX3;
|
| Genbank Protein ID |
NP_010267.3;
|
| Genbank Nucleotide ID |
NM_001180076.3;
|
| Protein Name |
Cell division control protein 7 |
| Protein Synonyms/Alias |
|
| Gene Name |
CDC7 |
| Gene Synonyms/Alias |
OAF2;YDL017W;D2855; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Serine/threonine-protein kinase. Needed for the initiation of DNA synthesis during mitosis as well as for synaptonemal complex formation and commitment to recombination during meiosis. Required for HTA1-HTB1 locus transcription repression.Functional Description
Serine/threonine-protein kinase. Needed for the initiation of DNA synthesis during mitosis as well as for synaptonemal complex formation and commitment to recombination during meiosis. Required for HTA1-HTB1 locus transcription repression. |
Phosphorylation Sites
|
dbPAF PTMs: 7 |
Sequence
(Fasta) | MTSKTKNIDD IPPEIKEEMI QLYHDLPGIE NEYKLIDKIG EGTFSSVYKA KDITGKITKK 60
FASHFWNYGS NYVALKKIYV TSSPQRIYNE LNLLYIMTGS SRVAPLCDAK RVRDQVIAVL 120
PYYPHEEFRT FYRDLPIKGI KKYIWELLRA LKFVHSKGII HRDIKPTNFL FNLELGRGVL 180
VDFGLAEAQM DYKSMISSQN DYDNYANTNH DGGYSMRNHE QFCPCIMRNQ YSPNSHNQTP 240
PMVTIQNGKV VHLNNVNGVD LTKGYPKNET RRIKRANRAG TRGFRAPEVL MKCGAQSTKI 300
DIWSVGVILL SLLGRRFPMF QSLDDADSLL ELCTIFGWKE LRKCAALHGL GFEASGLIWD 360
KPNGYSNGLK EFVYDLLNKE CTIGTFPEYS VAFETFGFLQ QELHDRMSIE PQLPDPKTNM 420
DAVDAYELKK YQEEIWSDHY WCFQVLEQCF EMDPQKRSSA EDLLKTPFFN ELNENTYLLD 480
GESTDEDDVV SSSEADLLDK DVLLISE
508Fasta Sequence
>P06243|CDC7|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MTSKTKNIDDIPPEIKEEMIQLYHDLPGIENEYKLIDKIGEGTFSSVYKAKDITGKITKKFASHFWNYGSNYVALKKIYVTSSPQRIYNELNLLYIMTGSSRVAPLCDAKRVRDQVIAVLPYYPHEEFRTFYRDLPIKGIKKYIWELLRALKFVHSKGIIHRDIKPTNFLFNLELGRGVLVDFGLAEAQMDYKSMISSQNDYDNYANTNHDGGYSMRNHEQFCPCIMRNQYSPNSHNQTPPMVTIQNGKVVHLNNVNGVDLTKGYPKNETRRIKRANRAGTRGFRAPEVLMKCGAQSTKIDIWSVGVILLSLLGRRFPMFQSLDDADSLLELCTIFGWKELRKCAALHGLGFEASGLIWDKPNGYSNGLKEFVYDLLNKECTIGTFPEYSVAFETFGFLQQELHDRMSIEPQLPDPKTNMDAVDAYELKKYQEEIWSDHYWCFQVLEQCFEMDPQKRSSAEDLLKTPFFNELNENTYLLDGESTDEDDVVSSSEADLLDKDVLLISE
|
| Keyword |
KW-0067--ATP-binding
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0418--Kinase
KW-0460--Magnesium
KW-0469--Meiosis
KW-0479--Metal-binding
KW-0498--Mitosis
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
|
| Interpro |
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
|
| PROSITE |
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
|
| Pfam |
PF00069--Pkinase
|
| Gene Ontology |
GO:0000775--C:chromosome, centromeric region
GO:0005737--C:cytoplasm
GO:0031431--C:Dbf4-dependent protein kinase complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0042802--F:identical protein binding
GO:0046872--F:metal ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0051301--P:cell division
GO:0006270--P:DNA replication initiation
GO:0000727--P:double-strand break repair via break-induced replication
GO:0007067--P:mitotic nuclear division
GO:0001100--P:negative regulation of exit from mitosis
GO:0018105--P:peptidyl-serine phosphorylation
GO:0006909--P:phagocytosis
GO:0060903--P:positive regulation of meiosis I
GO:1903343--P:positive regulation of meiotic DNA double-strand break formation
GO:0006279--P:premeiotic DNA replication
GO:0006468--P:protein phosphorylation
GO:0008360--P:regulation of cell shape
GO:0031938--P:regulation of chromatin silencing at telomere
|
