dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004407
Uniprot Accession P06168; ILV5_YEAST; D6VYZ3;
Genbank Protein ID NP_013459.1;
Genbank Nucleotide ID NM_001182244.1;
Protein Name Ketol-acid reductoisomerase, mitochondrial
Protein Synonyms/Alias Acetohydroxy-acid reductoisomerase;Alpha-keto-beta-hydroxylacyl reductoisomerase;
Gene Name ILV5
Gene Synonyms/Alias YLR355C;L9638.7;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 18
PositionPeptidesSourceReferences ( PMIDs )
85DTFALIGYGSQGYGQdbPTM 3.0;SysPTM 2.018407956; 16381945; 23193290; 19366988
139EDAIKRGSYVMNLLScurated25521595
153SDAAQSETWPAIKPLcurated25521595
166PLLTKGKTLYFSHGFPhosphoPep 2.0;curated19060867; 22817900; 20377248
168LTKGKTLYFSHGFSPPhosphoPep 2.019060867
174LYFSHGFSPVFKDLTPhosphoPep 2.019060867
199ILVAPKGSGRTVRSLPhosphoPep 2.019060867
217GRGINSSYAVWNDVTcurated25315811
284VLRENGHSPSEAFNEcurated23607784
292PSEAFNETVEEATQScurated26040289
317DYMYDACSTTARRGAdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 26040289; 25315811
318YMYDACSTTARRGALdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
343KPVFQDLYESTKNGTPhosphoPep 2.019060867
345VFQDLYESTKNGTETPhosphoPep 2.019060867
346FQDLYESTKNGTETKPhosphoPep 2.0;curated19060867; 22369663
350YESTKNGTETKRSLEPhosphoPep 2.019060867
355NGTETKRSLEFNSQPdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 20702584; 19779198; 19060867;
360KRSLEFNSQPDYREKPhosphoGRID 2.0;curated19779198; 22369663; 22817900
Sequence
(Fasta)		MLRTQAARLI CNSRVITAKR TFALATRAAA YSRPAARFVK PMITTRGLKQ INFGGTVETV 60
YERADWPREK LLDYFKNDTF ALIGYGSQGY GQGLNLRDNG LNVIIGVRKD GASWKAAIED 120
GWVPGKNLFT VEDAIKRGSY VMNLLSDAAQ SETWPAIKPL LTKGKTLYFS HGFSPVFKDL 180
THVEPPKDLD VILVAPKGSG RTVRSLFKEG RGINSSYAVW NDVTGKAHEK AQALAVAIGS 240
GYVYQTTFER EVNSDLYGER GCLMGGIHGM FLAQYDVLRE NGHSPSEAFN ETVEEATQSL 300
YPLIGKYGMD YMYDACSTTA RRGALDWYPI FKNALKPVFQ DLYESTKNGT ETKRSLEFNS 360
QPDYREKLEK ELDTIRNMEI WKVGKEVRKL RPENQ 396
Keyword

KW-0028--Amino-acid biosynthesis
KW-0100--Branched-chain amino acid biosynthesis
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0496--Mitochondrion
KW-0521--NADP
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0809--Transit peptide
Interpro

IPR008927--6-PGluconate_DH_C-like
IPR013328--6PGD_dom_2
IPR000506--AcH_isomrdctse_C
IPR013116--IlvN
IPR013023--Ketol-acid_reductoisomrdctse
IPR016207--KetolA_reductoisomerase_fun
IPR016040--NAD(P)-bd_dom
PROSITE
Pfam

PF01450--IlvC
PF07991--IlvN
Gene Ontology

GO:0042645--C:mitochondrial nucleoid
GO:0005739--C:mitochondrion
GO:0003690--F:double-stranded DNA binding
GO:0004455--F:ketol-acid reductoisomerase activity
GO:0046872--F:metal ion binding
GO:0009082--P:branched-chain amino acid biosynthetic process
GO:0009097--P:isoleucine biosynthetic process
GO:0000002--P:mitochondrial genome maintenance
GO:0009099--P:valine biosynthetic process