dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004401
Uniprot Accession P06106; MET17_YEAST; D6VYU6;
Genbank Protein ID NP_013406.1;
Genbank Nucleotide ID NM_001182191.1;
Protein Name Protein MET17
Protein Synonyms/Alias
Gene Name MET17
Gene Synonyms/Alias MET25;YLR303W;L8003.1;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Transforms O-acetylhomoserine into homocysteine and O-acetylserine into cysteine.
Phosphorylation Sites
 dbPAF PTMs: 6
PositionPeptidesSourceReferences ( PMIDs )
30RSRAVPIYATTSYVFcurated22817900
34VPIYATTSYVFENSKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22817900
35PIYATTSYVFENSKHdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
44FENSKHGSQLFGLEVdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 17563356; 18407956; 16381945; 23193290; 19060867;
63YSRFQNPTSNVLEERdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
377VDNLKLASNLANVGDdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
Sequence
(Fasta)		MPSHFDTVQL HAGQENPGDN AHRSRAVPIY ATTSYVFENS KHGSQLFGLE VPGYVYSRFQ 60
NPTSNVLEER IAALEGGAAA LAVSSGQAAQ TLAIQGLAHT GDNIVSTSYL YGGTYNQFKI 120
SFKRFGIEAR FVEGDNPEEF EKVFDERTKA VYLETIGNPK YNVPDFEKIV AIAHKHGIPV 180
VVDNTFGAGG YFCQPIKYGA DIVTHSATKW IGGHGTTIGG IIVDSGKFPW KDYPEKFPQF 240
SQPAEGYHGT IYNEAYGNLA YIVHVRTELL RDLGPLMNPF ASFLLLQGVE TLSLRAERHG 300
ENALKLAKWL EQSPYVSWVS YPGLASHSHH ENAKKYLSNG FGGVLSFGVK DLPNADKETD 360
PFKLSGAQVV DNLKLASNLA NVGDAKTLVI APYFTTHKQL NDKEKLASGV TKDLIRVSVG 420
IEFIDDIIAD FQQSFETVFA GQKP 445
Keyword

KW-0028--Amino-acid biosynthesis
KW-0181--Complete proteome
KW-0198--Cysteine biosynthesis
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0486--Methionine biosynthesis
KW-0511--Multifunctional enzyme
KW-0597--Phosphoprotein
KW-0663--Pyridoxal phosphate
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR000277--Cys/Met-Metab_PyrdxlP-dep_enz
IPR006235--OAc-hSer/O-AcSer_sulfhydrylase
IPR015424--PyrdxlP-dep_Trfase
IPR015421--PyrdxlP-dep_Trfase_major_sub1
IPR015422--PyrdxlP-dep_Trfase_major_sub2
PROSITE

PS00868--CYS_MET_METAB_PP
Pfam

PF01053--Cys_Met_Meta_PP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0004124--F:cysteine synthase activity
GO:0003961--F:O-acetylhomoserine aminocarboxypropyltransferase activity
GO:0030170--F:pyridoxal phosphate binding
GO:0071266--P:'de novo' L-methionine biosynthetic process
GO:0019344--P:cysteine biosynthetic process
GO:0006555--P:methionine metabolic process