dbPAF Protein Information
| Tag | Content | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0004326 | ||||||||||||
| Uniprot Accession | P05373; HEM2_YEAST; D6VU99; | ||||||||||||
| Genbank Protein ID | NP_011475.1; | ||||||||||||
| Genbank Nucleotide ID | NM_001180905.1; | ||||||||||||
| Protein Name | Delta-aminolevulinic acid dehydratase | ||||||||||||
| Protein Synonyms/Alias | |||||||||||||
| Gene Name | HEM2 | ||||||||||||
| Gene Synonyms/Alias | YGL040C; | ||||||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||||||
| NCBI Taxa ID | 559292 | ||||||||||||
| Functional Description (View all) |
Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. | ||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 2
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| Sequence (Fasta) | MHTAEFLETE PTEISSVLAG GYNHPLLRQW QSERQLTKNM LIFPLFISDN PDDFTEIDSL 60 PNINRIGVNR LKDYLKPLVA KGLRSVILFG VPLIPGTKDP VGTAADDPAG PVIQGIKFIR 120 EYFPELYIIC DVCLCEYTSH GHCGVLYDDG TINRERSVSR LAAVAVNYAK AGAHCVAPSD 180 MIDGRIRDIK RGLINANLAH KTFVLSYAAK FSGNLYGPFR DAACSAPSNG DRKCYQLPPA 240 GRGLARRALE RDMSEGADGI IVKPSTFYLD IMRDASEICK DLPICAYHVS GEYAMLHAAA 300 EKGVVDLKTI AFESHQGFLR AGARLIITYL APEFLDWLDE EN 343 |
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| Keyword | KW-0002--3D-structure |
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| Interpro | |||||||||||||
| PROSITE | PS00169--D_ALA_DEHYDRATASE |
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| Pfam | PF00490--ALAD |
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| Gene Ontology | GO:0005829--C:cytosol |