dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004316
Uniprot Accession P05303; EF1A2_DROME; Q9V9U8;
Genbank Protein ID NP_524611.1; NP_733449.1; NP_996315.1; NP_996316.1;
Genbank Nucleotide ID NM_079872.4; NM_170570.1; NM_206592.1; NM_206593.1;
Protein Name Elongation factor 1-alpha 2
Protein Synonyms/Alias
Gene Name Ef1alpha100E
Gene Synonyms/Alias EF1a;F2;CG1873;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
29TTTGHLIYKCGGIDKPHOSIDA;curated21081558; 22817900
Sequence
(Fasta)
MGKEKIHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAQEMG KGSFKYAWVL 60
DKLKAERERG ITIDIALWKF ETSKYYVTII DAPGHRDFIK NMITGTSQAD CAVLIVAAGT 120
GEFEAGISKN GQTREHALLA FTLGVKQLIV GVNKMDSTEP PYSEARYEEI KKEVSSYIKK 180
IGYNPASVAF VPISGWHGDN MLEPSEKMPW FKGWSVERKE GKAEGKCLID ALDAILPPQR 240
PTDKPLRLPL QDVYKIGGIG TVPVGRVETG LLKPGMVVNF APVNLVTEVK SVEMHHEALT 300
EAMPGDNVGF NVKNVSVKEL RRGYVAGDSK NNPPRGAADF TAQVIVLNHP GQIANGYTPV 360
LDCHTAHIAC KFSEIKEKCD RRTGKTTETE PKAIKSGDAA IIVLVPSKPL CVESFQEFPP 420
LGRFAVRDMR QTVAVGVIKS VNFKETTSGK VTKAAEKAQK KK 463
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0251--Elongation factor
KW-0342--GTP-binding
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome

Interpro

IPR031157--G_TR_CS
IPR027417--P-loop_NTPase
IPR000795--TF_GTP-bd_dom
IPR009000--Transl_B-barrel
IPR009001--Transl_elong_EF1A/Init_IF2_C
IPR004539--Transl_elong_EF1A_euk/arc
IPR004161--Transl_elong_EFTu/EF1A_2
IPR004160--Transl_elong_EFTu/EF1A_C

PROSITE

PS00301--G_TR_1
PS51722--G_TR_2

Pfam

PF03144--GTP_EFTU_D2
PF03143--GTP_EFTU_D3

Gene Ontology

GO:0005853--C:eukaryotic translation elongation factor 1 complex
GO:0005811--C:lipid particle
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0003746--F:translation elongation factor activity
GO:0022008--P:neurogenesis
GO:0006414--P:translational elongation