Functional Description
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Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.Functional Description
Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. |
| Gene Ontology |
GO:0005694--C:chromosome
GO:0000775--C:chromosome, centromeric region
GO:0000781--C:chromosome, telomeric region
GO:0000793--C:condensed chromosome
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0000791--C:euchromatin
GO:0000792--C:heterochromatin
GO:0005720--C:nuclear heterochromatin
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005721--C:pericentric heterochromatin
GO:0005700--C:polytene chromosome
GO:0005704--C:polytene chromosome band
GO:0005701--C:polytene chromosome chromocenter
GO:0005703--C:polytene chromosome puff
GO:0035012--C:polytene chromosome, telomeric region
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0035064--F:methylated histone binding
GO:0003729--F:mRNA binding
GO:0000182--F:rDNA binding
GO:0003723--F:RNA binding
GO:0003696--F:satellite DNA binding
GO:0006342--P:chromatin silencing
GO:0030702--P:chromatin silencing at centromere
GO:0051276--P:chromosome organization
GO:0044026--P:DNA hypermethylation
GO:0006343--P:establishment of chromatin silencing
GO:0016458--P:gene silencing
GO:0031507--P:heterochromatin assembly
GO:0034773--P:histone H4-K20 trimethylation
GO:0007067--P:mitotic nuclear division
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0022008--P:neurogenesis
GO:0033697--P:positive regulation of extent of heterochromatin assembly
GO:1900111--P:positive regulation of histone H3-K9 dimethylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0042981--P:regulation of apoptotic process
GO:0031060--P:regulation of histone methylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0000723--P:telomere maintenance
GO:0006351--P:transcription, DNA-templated
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