dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004269
Uniprot Accession P05084; HUNB_DROME; Q24018; Q29R06; Q960U7;
Genbank Protein ID NP_731267.1; NP_731268.1;
Genbank Nucleotide ID NM_169233.2; NM_169234.2;
Protein Name Protein hunchback
Protein Synonyms/Alias
Gene Name hb
Gene Synonyms/Alias CG9786;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
Gap class segmentation protein that controls development of head structures.
Phosphorylation Sites
dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
178SEKLQALTPPMDVTPdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
188MDVTPPKSPAKSSQSdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
207EKEHDQMSNSSEDMKdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
209EHDQMSNSSEDMKYMdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
210HDQMSNSSEDMKYMAdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
219DMKYMAESEDDDTNIdbPTM 3.0;SysPTM 2.0;curated18327897; 16381945; 23193290; 19366988; 22817900
537DDEYERKSVDSAMDLdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
540YERKSVDSAMDLSQGdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;UniProt;curated18327897; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MQNWETTATT NYEQHNAWYN SMFAANIKQE PGHHLDGNSV ASSPRQSPIP STNHLEQFLK 60
QQQQQLQQQP MDTLCAMTPS PSQNDQNSLQ HYDANLQQQL LQQQQYQQHF QAAQQQHHHH 120
HHLMGGFNPL TPPGLPNPMQ HFYGGNLRPS PQPTPTSAST IAPVAVATGS SEKLQALTPP 180
MDVTPPKSPA KSSQSNIEPE KEHDQMSNSS EDMKYMAESE DDDTNIRMPI YNSHGKMKNY 240
KCKTCGVVAI TKVDFWAHTR THMKPDKILQ CPKCPFVTEF KHHLEYHIRK HKNQKPFQCD 300
KCSYTCVNKS MLNSHRKSHS SVYQYRCADC DYATKYCHSF KLHLRKYGHK PGMVLDEDGT 360
PNPSLVIDVY GTRRGPKSKN GGPIASGGSG SGSRKSNVAA VAPQQQQSQP AQPVATSQLS 420
AALQGFPLVQ GNSAPPAASP VLPLPASPAK SVASVEQTPS LPSPANLLPP LASLLQQNRN 480
MAFFPYWNLN LQMLAAQQQA AVLAQLSPRM REQLQQQNQQ QSDNEEEEQD DEYERKSVDS 540
AMDLSQGTPV KEDEQQQQPQ QPLAMNLKVE EEATPLMSSS NASRRKGRVL KLDTLLQLRS 600
EAMTSPEQLK VPSTPMPTAS SPIAGRKPMP EEHCSGTSSA DESMETAHVP QANTSASSTA 660
SSSGNSSNAS SNSNGNSSSN SSSNGTTSAV AAPPSGTPAA AGAIYECKYC DIFFKDAVLY 720
TIHMGYHSCD DVFKCNMCGE KCDGPVGLFV HMARNAHS 759
Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0302--Gap protein
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027775--C2H2_Znf_fam
IPR027742--Hunchback
IPR007087--Znf_C2H2
IPR015880--Znf_C2H2-like
IPR013087--Znf_C2H2/integrase_DNA-bd

PROSITE

PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam
Gene Ontology

GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003705--F:transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0007355--P:anterior region determination
GO:0008595--P:anterior/posterior axis specification, embryo
GO:0007427--P:epithelial cell migration, open tracheal system
GO:0007402--P:ganglion mother cell fate determination
GO:0048699--P:generation of neurons
GO:0001763--P:morphogenesis of a branching structure
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0007400--P:neuroblast fate determination
GO:0007424--P:open tracheal system development
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0035289--P:posterior head segmentation
GO:0040034--P:regulation of development, heterochronic
GO:0044324--P:regulation of transcription involved in anterior/posterior axis specification
GO:0007431--P:salivary gland development
GO:0007362--P:terminal region determination
GO:0008293--P:torso signaling pathway
GO:0006351--P:transcription, DNA-templated
GO:0035290--P:trunk segmentation
GO:0007419--P:ventral cord development
GO:0007354--P:zygotic determination of anterior/posterior axis, embryo