dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0004246 | ||||||||
| Uniprot Accession | P04912; H2A2_YEAST; D6VPZ9; | ||||||||
| Genbank Protein ID | NP_009552.1; | ||||||||
| Genbank Nucleotide ID | NM_001178243.1; | ||||||||
| Protein Name | Histone H2A.2 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | HTA2 | ||||||||
| Gene Synonyms/Alias | H2A2;YBL003C;YBL0103; | ||||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||
| NCBI Taxa ID | 559292 | ||||||||
| Functional Description (View all) |
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MSGGKGGKAG SAAKASQSRS AKAGLTFPVG RVHRLLRRGN YAQRIGSGAP VYLTAVLEYL 60 AAEILELAGN AARDNKKTRI IPRHLQLAIR NDDELNKLLG NVTIAQGGVL PNIHQNLLPK 120 KSAKTAKASQ EL 133 |
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| Keyword | KW-0002--3D-structure |
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| Interpro | IPR009072--Histone-fold |
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| PROSITE | PS00046--HISTONE_H2A |
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| Pfam | |||||||||
| Gene Ontology | GO:0000788--C:nuclear nucleosome |