dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004225
Uniprot Accession P04802; SYDC_YEAST; D6VXY6;
Genbank Protein ID NP_013083.1;
Genbank Nucleotide ID NM_001181838.1;
Protein Name Aspartate--tRNA ligase, cytoplasmic
Protein Synonyms/Alias Aspartyl-tRNA synthetase;AspRS;
Gene Name DPS1
Gene Synonyms/Alias APS;APS1;YLL018C;L1295;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 13
PositionPeptidesSourceReferences ( PMIDs )
2------MSQDENIVKPhosphoGRID 2.0;PHOSIDA;curated19823750; 19795423; 21081558; 26040406; 22369663
14IVKAVEESAEPAQVIdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 21177495; 19060867;
30GEDGKPLSKKALKKLcurated24961812; 25315811
105DLDEAKDSDKEVLFRcurated25315811
196IHITKIYTISETPEAPhosphoGRID 2.021126336
214LLEDASRSEAEAEAAcurated22369663; 25315811
243VIDLRTVTNQAIFRIdbPTM 3.0;SysPTM 2.018407956; 16381945; 23193290; 19366988
272KKFTEVHTPKLLGAPcurated25315811
301GKAYLAQSPQFNKQQdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated15665377; 17330950; 18407956; 16381945; 23193290; 21177495;
329PVFRAENSNTHRHMTcurated25315811
481MRGEEILSGAQRIHDcurated25315811
502RMKAHGLSPEDPGLKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 19366988; 22369663;
546LKNIRRASLFPRDPKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17287358; 18407956; 16381945; 23193290; 19779198; 19366988;
Sequence
(Fasta)		MSQDENIVKA VEESAEPAQV ILGEDGKPLS KKALKKLQKE QEKQRKKEER ALQLEAEREA 60
REKKAAAEDT AKDNYGKLPL IQSRDSDRTG QKRVKFVDLD EAKDSDKEVL FRARVHNTRQ 120
QGATLAFLTL RQQASLIQGL VKANKEGTIS KNMVKWAGSL NLESIVLVRG IVKKVDEPIK 180
SATVQNLEIH ITKIYTISET PEALPILLED ASRSEAEAEA AGLPVVNLDT RLDYRVIDLR 240
TVTNQAIFRI QAGVCELFRE YLATKKFTEV HTPKLLGAPS EGGSSVFEVT YFKGKAYLAQ 300
SPQFNKQQLI VADFERVYEI GPVFRAENSN THRHMTEFTG LDMEMAFEEH YHEVLDTLSE 360
LFVFIFSELP KRFAHEIELV RKQYPVEEFK LPKDGKMVRL TYKEGIEMLR AAGKEIGDFE 420
DLSTENEKFL GKLVRDKYDT DFYILDKFPL EIRPFYTMPD PANPKYSNSY DFFMRGEEIL 480
SGAQRIHDHA LLQERMKAHG LSPEDPGLKD YCDGFSYGCP PHAGGGIGLE RVVMFYLDLK 540
NIRRASLFPR DPKRLRP 558
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0030--Aminoacyl-tRNA synthetase
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
Interpro

IPR004364--aa-tRNA-synt_II
IPR018150--aa-tRNA-synt_II-like
IPR006195--aa-tRNA-synth_II
IPR004523--Asp-tRNA_synthase_arc
IPR002312--Asp/Asn-tRNA-synth_IIb
IPR012340--NA-bd_OB-fold
IPR004365--NA-bd_OB_tRNA
PROSITE

PS50862--AA_TRNA_LIGASE_II
Pfam

PF00152--tRNA-synt_2
PF01336--tRNA_anti-codon
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004815--F:aspartate-tRNA ligase activity
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0006422--P:aspartyl-tRNA aminoacylation