| Tag |
Content |
| dbPAF ID |
dbPAF-0004183 |
| Uniprot Accession |
P04387; GAL80_YEAST; D6VZC4;
|
| Genbank Protein ID |
NP_013661.1;
|
| Genbank Nucleotide ID |
NM_001182409.1;
|
| Protein Name |
Galactose/lactose metabolism regulatory protein GAL80 |
| Protein Synonyms/Alias |
|
| Gene Name |
GAL80 |
| Gene Synonyms/Alias |
YML051W;YM9827.01;YM9958.12; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
This protein is a negative regulator for the gene expression of the lactose/galactose metabolic genes. It binds to GAL4 and so blocks transcriptional activation by it, in the absence of an inducing sugar.Functional Description
This protein is a negative regulator for the gene expression of the lactose/galactose metabolic genes. It binds to GAL4 and so blocks transcriptional activation by it, in the absence of an inducing sugar. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MDYNKRSSVS TVPNAAPIRV GFVGLNAAKG WAIKTHYPAI LQLSSQFQIT ALYSPKIETS 60
IATIQRLKLS NATAFPTLES FASSSTIDMI VIAIQVASHY EVVMPLLEFS KNNPNLKYLF 120
VEWALACSLD QAESIYKAAA ERGVQTIISL QGRKSPYILR AKELISQGYI GDINSIEIAG 180
NGGWYGYERP VKSPKYIYEI GNGVDLVTTT FGHTIDILQY MTSSYFSRIN AMVFNNIPEQ 240
ELIDERGNRL GQRVPKTVPD HLLFQGTLLN GNVPVSCSFK GGKPTKKFTK NLVIDIHGTK 300
GDLKLEGDAG FAEISNLVLY YSGTRANDFP LANGQQAPLD PGYDAGKEIM EVYHLRNYNA 360
IVGNIHRLYQ SISDFHFNTK KIPELPSQFV MQGFDFEGFP TLMDALILHR LIESVYKSNM 420
MGSTLNVSNI SHYSL
436Fasta Sequence
>P04387|GAL80|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MDYNKRSSVSTVPNAAPIRVGFVGLNAAKGWAIKTHYPAILQLSSQFQITALYSPKIETSIATIQRLKLSNATAFPTLESFASSSTIDMIVIAIQVASHYEVVMPLLEFSKNNPNLKYLFVEWALACSLDQAESIYKAAAERGVQTIISLQGRKSPYILRAKELISQGYIGDINSIEIAGNGGWYGYERPVKSPKYIYEIGNGVDLVTTTFGHTIDILQYMTSSYFSRINAMVFNNIPEQELIDERGNRLGQRVPKTVPDHLLFQGTLLNGNVPVSCSFKGGKPTKKFTKNLVIDIHGTKGDLKLEGDAGFAEISNLVLYYSGTRANDFPLANGQQAPLDPGYDAGKEIMEVYHLRNYNAIVGNIHRLYQSISDFHFNTKKIPELPSQFVMQGFDFEGFPTLMDALILHRLIESVYKSNMMGSTLNVSNISHYSL
|
| Keyword |
KW-0002--3D-structure
KW-0007--Acetylation
KW-0119--Carbohydrate metabolism
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0238--DNA-binding
KW-0299--Galactose metabolism
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
|
| Interpro |
IPR016040--NAD(P)-bd_dom
IPR000683--Oxidoreductase_N
|
| PROSITE |
|
| Pfam |
PF01408--GFO_IDH_MocA
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0019210--F:kinase inhibitor activity
GO:0016491--F:oxidoreductase activity
GO:0001102--F:RNA polymerase II activating transcription factor binding
GO:0006012--P:galactose metabolic process
GO:0033673--P:negative regulation of kinase activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0055114--P:oxidation-reduction process
GO:0006351--P:transcription, DNA-templated
|
