dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0004103
Uniprot Accession P03965; CARB_YEAST; D6VWS8;
Genbank Protein ID NP_012643.3;
Genbank Nucleotide ID NM_001181767.3;
Protein Name Carbamoyl-phosphate synthase arginine-specific large chain
Protein Synonyms/Alias Arginine-specific carbamoyl-phosphate synthetase, ammonia chain;
Gene Name CPA2
Gene Synonyms/Alias YJR109C;J2002;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
2------MTSIYTSTEcurated19823750
3-----MTSIYTSTEPcurated19823750
6--MTSIYTSTEPTNScurated19823750
17PTNSAFTTEDYKPQLcurated19823750
525VTINKHASTNINELEcurated22369663
551PFVKRIDTLAAEFPAcurated22369663
761KAKLTLASDVSPDHPcurated25704821
764LTLASDVSPDHPVVMcurated25704821
Sequence
(Fasta)		MTSIYTSTEP TNSAFTTEDY KPQLVEGVNS VLVIGSGGLS IGQAGEFDYS GSQAIKALKE 60
DNKFTILVNP NIATNQTSHS LADKIYYLPV TPEYITYIIE LERPDAILLT FGGQTGLNCG 120
VALDESGVLA KYNVKVLGTP IKTLITSEDR DLFASALKDI NIPIAESFAC ETVDEALEAA 180
ERVKYPVIVR SAYALGGLGS GFANNASEMK ELAAQSLSLA PQILVEKSLK GWKEVEYEVV 240
RDRVGNCITV CNMENFDPLG VHTGDSMVFA PSQTLSDEEF HMLRSAAIKI IRHLGVIGEC 300
NVQYALQPDG LDYRVIEVNA RLSRSSALAS KATGYPLAYT AAKIGLGYTL PELPNPITKT 360
TVANFEPSLD YIVAKIPKWD LSKFQYVDRS IGSSMKSVGE VMAIGRNYEE AFQKALRQVD 420
PSLLGFQGST EFGDQLDEAL RTPTDRRVLA IGQALIHENY TVERVNELSK IDKWFLYKCM 480
NIVNIYKELE SVKSLSDLSK DLLQRAKKLG FSDKQIAVTI NKHASTNINE LEIRSLRKTL 540
GIIPFVKRID TLAAEFPAQT NYLYTTYNAT KNDVEFNENG MLVLGSGVYR IGSSVEFDWC 600
AVNTAKTLRD QGKKTIMINY NPETVSTDFD EVDRLYFEEL SYERVMDIYE LEQSEGCIIS 660
VGGQLPQNIA LKLYDNGCNI MGTNPNDIDR AENRHKFSSI LDSIDVDQPE WSELTSVEEA 720
KLFASKVNYP VLIRPSYVLS GAAMSVVNNE EELKAKLTLA SDVSPDHPVV MSKFIEGAQE 780
IDVDAVAYNG NVLVHAISEH VENAGVHSGD ASLVLPPQHL SDDVKIALKD IADKVAKAWK 840
ITGPFNMQII KDGEHTLKVI ECNIRASRSF PFVSKVLGVN FIEIAVKAFL GGDIVPKPVD 900
LMLNKKYDYV ATKVPQFSFT RLAGADPFLG VEMASTGEVA SFGRDLIESY WTAIQSTMNF 960
HVPLPPSGIL FGGDTSREYL GQVASIVATI GYRIYTTNET TKTYLQEHIK EKNAKVSLIK 1020
FPKNDKRKLR ELFQEYDIKA VFNLASKRAE STDDVDYIMR RNAIDFAIPL FNEPQTALLF 1080
AKCLKAKIAE KIKILESHDV IVPPEVRSWD EFIGFKAY 1119
Keyword

KW-0028--Amino-acid biosynthesis
KW-0055--Arginine biosynthesis
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0436--Ligase
KW-0464--Manganese
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011761--ATP-grasp
IPR013815--ATP_grasp_subdomain_1
IPR013816--ATP_grasp_subdomain_2
IPR006275--CarbamoylP_synth_lsu
IPR005480--CarbamoylP_synth_lsu_oligo
IPR005479--CbamoylP_synth_lsu-like_ATP-bd
IPR005483--CbamoylP_synth_lsu_CPSase_dom
IPR011607--MGS-like_dom
IPR016185--PreATP-grasp_dom
PROSITE

PS50975--ATP_GRASP
PS00866--CPSASE_1
PS00867--CPSASE_2
Pfam

PF02786--CPSase_L_D2
PF02787--CPSase_L_D3
PF02142--MGS
Gene Ontology

GO:0005951--C:carbamoyl-phosphate synthase complex
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004087--F:carbamoyl-phosphate synthase (ammonia) activity
GO:0004088--F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0046872--F:metal ion binding
GO:0006207--P:'de novo' pyrimidine nucleobase biosynthetic process
GO:0006526--P:arginine biosynthetic process
GO:0000050--P:urea cycle