dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004102
Uniprot Accession P03962; PYRF_YEAST; D3DLM7;
Genbank Protein ID NP_010893.3;
Genbank Nucleotide ID NM_001178836.3;
Protein Name Orotidine 5'-phosphate decarboxylase
Protein Synonyms/Alias OMP decarboxylase;OMPDCase;OMPdecase;Uridine 5'-monophosphate synthase;UMP synthase;
Gene Name URA3
Gene Synonyms/Alias YEL021W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
219ALGQQYRTVDDVVSTdbPTM 3.0;SysPTM 2.018407956; 16381945; 23193290; 19366988
228DDVVSTGSDIIIVGRdbPTM 3.0;SysPTM 2.018407956; 16381945; 23193290; 19366988
Sequence
(Fasta)
MSKATYKERA ATHPSPVAAK LFNIMHEKQT NLCASLDVRT TKELLELVEA LGPKICLLKT 60
HVDILTDFSM EGTVKPLKAL SAKYNFLLFE DRKFADIGNT VKLQYSAGVY RIAEWADITN 120
AHGVVGPGIV SGLKQAAEEV TKEPRGLLML AELSCKGSLA TGEYTKGTVD IAKSDKDFVI 180
GFIAQRDMGG RDEGYDWLIM TPGVGLDDKG DALGQQYRTV DDVVSTGSDI IIVGRGLFAK 240
GRDAKVEGER YRKAGWEAYL RRCGQQN 268
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0210--Decarboxylase
KW-1017--Isopeptide bond
KW-0456--Lyase
KW-0665--Pyrimidine biosynthesis
KW-1185--Reference proteome
KW-0832--Ubl conjugation

Interpro

IPR013785--Aldolase_TIM
IPR014732--OMPdecase
IPR018089--OMPdecase_AS
IPR001754--OMPdeCOase_dom
IPR011060--RibuloseP-bd_barrel

PROSITE

PS00156--OMPDECASE

Pfam

PF00215--OMPdecase

Gene Ontology

GO:0005829--C:cytosol
GO:0004590--F:orotidine-5'-phosphate decarboxylase activity
GO:0006207--P:'de novo' pyrimidine nucleobase biosynthetic process
GO:0044205--P:'de novo' UMP biosynthetic process
GO:0006222--P:UMP biosynthetic process