dbPAF Protein Information
Tag | Content | ||||||||||||
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dbPAF ID | dbPAF-0004085 | ||||||||||||
Uniprot Accession | P03877; SCE3_YEAST; A0A0A7P044; Q35790; Q9ZZX3; | ||||||||||||
Genbank Protein ID | NP_009308.2; | ||||||||||||
Genbank Nucleotide ID | NC_001224.1; | ||||||||||||
Protein Name | Intron-encoded DNA endonuclease aI3 | ||||||||||||
Protein Synonyms/Alias | DNA endonuclease I-SceIII; | ||||||||||||
Gene Name | AI3 | ||||||||||||
Gene Synonyms/Alias | ENS3;I-SCEIII;Q0060; | ||||||||||||
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) | ||||||||||||
NCBI Taxa ID | 559292 | ||||||||||||
Functional Description (View all) |
Mitochondrial DNA endonuclease involved in intron homing. It introduces a specific double-strand break in the DNA of the COX1 gene and thus mediates the insertion of an intron, containing its own coding sequence (group I intron), into an intronless gene. Recognizes with high specificity and cleaves the sequence 5'-GGTTTTGGTAACTATTTATTAC-3'. | ||||||||||||
Phosphorylation Sites |
dbPAF PTMs: 2
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Sequence (Fasta) | MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG NSQLFNVLVV 60 GHAVLMIFFL VMPALIGGFG NQKRYESNNN NNQVMENKEY NLKLNYDKLG PYLAGLIEGD 120 GTITVQNSSS MKKSKYRPLI VVVFKLEDLE LANYLCNLTK CGKVYKKINR NYVLWTIHDL 180 KGVYTLLNII NGYMRTPKYE AFVRGAEFMN NYINSTTITH NKLKNMDNIK IKPLDTSDIG 240 SNAWLAGMTD ADGNFSINLM NGKNRSSRAM PYYCLELRQN YQKNSNNNNI NFSYFYIMSA 300 IATYFNVNLY SRERNLNLLV STNNTYKTYY SYKVMVANTY KNIKVMEYFN KYSLLSSKHL 360 DFLDWSKLVI LINNEGQSMK TNGSWELGMN LRKDYNKTRT TFTWSHLKNT YLENK 416 |
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Keyword | KW-0181--Complete proteome |
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Interpro | IPR000883--COX1 |
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PROSITE | PS50855--COX1 |
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Pfam | |||||||||||||
Gene Ontology | GO:0016021--C:integral component of membrane |