Tag |
Content |
dbPAF ID |
dbPAF-0004079 |
Uniprot Accession |
P03069; GCN4_YEAST; D3DLN9; P03068; Q70D88; Q70D91; Q70D96; Q70D99; Q70DA0; Q96UT3; |
Genbank Protein ID |
NP_010907.3; |
Genbank Nucleotide ID |
NM_001178824.3; |
Protein Name |
General control protein GCN4 |
Protein Synonyms/Alias |
Amino acid biosynthesis regulatory protein; |
Gene Name |
GCN4 |
Gene Synonyms/Alias |
AAS3;ARG9;YEL009C; |
Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
NCBI Taxa ID |
559292 |
Functional Description (View all) |
Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.Functional Description
Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
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Phosphorylation Sites
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dbPAF PTMs: 6 |
Sequence (Fasta) | MSEYQPSLFA LNPMGFSPLD GSKSTNENVS ASTSTAKPMV GQLIFDKFIK TEEDPIIKQD 60 TPSNLDFDFA LPQTATAPDA KTVLPIPELD DAVVESFFSS STDSTPMFEY ENLEDNSKEW 120 TSLFDNDIPV TTDDVSLADK AIESTEEVSL VPSNLEVSTT SFLPTPVLED AKLTQTRKVK 180 KPNSVVKKSH HVGKDDESRL DHLGVVAYNR KQRSIPLSPI VPESSDPAAL KRARNTEAAR 240 RSRARKLQRM KQLEDKVEEL LSKNYHLENE VARLKKLVGE R
282Fasta Sequence
>P03069|GCN4|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) MSEYQPSLFALNPMGFSPLDGSKSTNENVSASTSTAKPMVGQLIFDKFIKTEEDPIIKQDTPSNLDFDFALPQTATAPDAKTVLPIPELDDAVVESFFSSSTDSTPMFEYENLEDNSKEWTSLFDNDIPVTTDDVSLADKAIESTEEVSLVPSNLEVSTTSFLPTPVLEDAKLTQTRKVKKPNSVVKKSHHVGKDDESRLDHLGVVAYNRKQRSIPLSPIVPESSDPAALKRARNTEAARRSRARKLQRMKQLEDKVEELLSKNYHLENEVARLKKLVGER
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Keyword |
KW-0002--3D-structure KW-0010--Activator KW-0028--Amino-acid biosynthesis KW-0181--Complete proteome KW-0238--DNA-binding KW-0539--Nucleus KW-0597--Phosphoprotein KW-1185--Reference proteome KW-0804--Transcription KW-0805--Transcription regulation
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Interpro |
IPR004827--bZIP
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PROSITE |
PS50217--BZIP PS00036--BZIP_BASIC
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Pfam |
PF07716--bZIP_2
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Gene Ontology |
GO:0000790--C:nuclear chromatin GO:0005654--C:nucleoplasm GO:0005634--C:nucleus GO:0005667--C:transcription factor complex GO:0003682--F:chromatin binding GO:0042802--F:identical protein binding GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0043565--F:sequence-specific DNA binding GO:0001135--F:transcription factor activity, RNA polymerase II transcription factor recruiting GO:0003700--F:transcription factor activity, sequence-specific DNA binding GO:0001084--F:transcription factor activity, TFIID-class binding GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding GO:0001191--F:transcriptional repressor activity, RNA polymerase II transcription factor binding GO:0008652--P:cellular amino acid biosynthetic process GO:0010691--P:negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter GO:0001080--P:nitrogen catabolite activation of transcription from RNA polymerase II promoter GO:1903833--P:positive regulation of cellular response to amino acid starvation GO:0045899--P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:0060261--P:positive regulation of transcription initiation from RNA polymerase II promoter GO:0010033--P:response to organic substance GO:0006366--P:transcription from RNA polymerase II promoter
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