dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0004073
Uniprot Accession P02835; FTZ_DROME; O96929; Q4V6Y3; Q9V3W3;
Genbank Protein ID NP_477498.1;
Genbank Nucleotide ID NM_058150.3;
Protein Name Segmentation protein fushi tarazu
Protein Synonyms/Alias
Gene Name ftz
Gene Synonyms/Alias CG2047;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)
May play a role in determining neuronal identity, may be directly involved in specifying identity of individual neurons. Required during embryogenesis for the process of body segmentation. Homeotic protein, required in alternating segment primordia, it specifies the correct number of segments.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
262KRTRQTYTRYQTLELdbPTM 3.0;Phospho.ELM 9.010370126; 9545243; 16381945; 23193290
Sequence
(Fasta)
MATTNSQSHY SYADNMNMYN MYHPHSLPPT YYDNSGSNAY YQNTSNYQGY YPQESYSESC 60
YYYNNQEQVT TQTVPPVQPT TPPPKATKRK AEDDAASIIA AVEERPSTLR ALLTNPVKKL 120
KYTPDYFYTT VEQVKKAPAV STKVTASPAP SYDQEYVTVP TPSASEDVDY LDVYSPQSQT 180
QKLKNGDFAT PPPTTPTSLP PLEGISTPPQ SPGEKSSSAV SQEINHRIVT APNGAGDFNW 240
SHIEETLASD CKDSKRTRQT YTRYQTLELE KEFHFNRYIT RRRRIDIANA LSLSERQIKI 300
WFQNRRMKSK KDRTLDSSPE HCGAGYTAML PPLEATSTAT TGAPSVPVPM YHHHQTTAAY 360
PAYSHSHSHG YGLLNDYPQQ QTHQQYDAYP QQYQHQCSYQ QHPQDLYHLS 411
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0371--Homeobox
KW-0539--Nucleus
KW-0562--Pair-rule protein
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR005567--FTZ_N
IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR020479--Homeobox_metazoa
IPR009057--Homeodomain-like

PROSITE

PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2

Pfam

PF03867--FTZ
PF00046--Homeobox

Gene Ontology

GO:0005634--C:nucleus
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003705--F:transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0007350--P:blastoderm segmentation
GO:0001708--P:cell fate specification
GO:0007417--P:central nervous system development
GO:0008354--P:germ cell migration
GO:0007506--P:gonadal mesoderm development
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0007366--P:periodic partitioning by pair rule gene
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0035289--P:posterior head segmentation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006355--P:regulation of transcription, DNA-templated
GO:0035282--P:segmentation
GO:0006366--P:transcription from RNA polymerase II promoter
GO:0035290--P:trunk segmentation