Tag |
Content |
dbPAF ID |
dbPAF-0004005 |
Uniprot Accession |
P02557; TBB_YEAST; D6VTJ3; |
Genbank Protein ID |
NP_116616.1; |
Genbank Nucleotide ID |
NM_001179929.1; |
Protein Name |
Tubulin beta chain |
Protein Synonyms/Alias |
Beta-tubulin; |
Gene Name |
TUB2 |
Gene Synonyms/Alias |
YFL037W; |
Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
NCBI Taxa ID |
559292 |
Functional Description (View all) |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.Functional Description
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
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Phosphorylation Sites
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dbPAF PTMs: 3 |
Sequence (Fasta) | MREIIHISTG QCGNQIGAAF WETICGEHGL DFNGTYHGHD DIQKERLNVY FNEASSGKWV 60 PRSINVDLEP GTIDAVRNSA IGNLFRPDNY IFGQSSAGNV WAKGHYTEGA ELVDSVMDVI 120 RREAEGCDSL QGFQITHSLG GGTGSGMGTL LISKIREEFP DRMMATFSVL PSPKTSDTVV 180 EPYNATLSVH QLVEHSDETF CIDNEALYDI CQRTLKLNQP SYGDLNNLVS SVMSGVTTSL 240 RYPGQLNSDL RKLAVNLVPF PRLHFFMVGY APLTAIGSQS FRSLTVPELT QQMFDAKNMM 300 AAADPRNGRY LTVAAFFRGK VSVKEVEDEM HKVQSKNSDY FVEWIPNNVQ TAVCSVAPQG 360 LDMAATFIAN STSIQELFKR VGDQFSAMFK RKAFLHWYTS EGMDELEFSE AESNMNDLVS 420 EYQQYQEATV EDDEEVDENG DFGAPQNQDE PITENFE
458Fasta Sequence
>P02557|TUB2|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQEATVEDDEEVDENGDFGAPQNQDEPITENFE
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Keyword |
KW-0002--3D-structure KW-0046--Antibiotic resistance KW-0181--Complete proteome KW-0963--Cytoplasm KW-0206--Cytoskeleton KW-0342--GTP-binding KW-0493--Microtubule KW-0547--Nucleotide-binding KW-0597--Phosphoprotein KW-1185--Reference proteome
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Interpro |
IPR013838--Beta-tubulin_BS IPR002453--Beta_tubulin IPR008280--Tub_FtsZ_C IPR000217--Tubulin IPR018316--Tubulin/FtsZ_2-layer-sand-dom IPR023123--Tubulin_C IPR017975--Tubulin_CS IPR003008--Tubulin_FtsZ_GTPase
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PROSITE |
PS00227--TUBULIN PS00228--TUBULIN_B_AUTOREG
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Pfam |
PF00091--Tubulin PF03953--Tubulin_C
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Gene Ontology |
GO:0005881--C:cytoplasmic microtubule GO:0005828--C:kinetochore microtubule GO:0005880--C:nuclear microtubule GO:0005816--C:spindle pole body GO:0045298--C:tubulin complex GO:0005525--F:GTP binding GO:0003924--F:GTPase activity GO:0005200--F:structural constituent of cytoskeleton GO:0045143--P:homologous chromosome segregation GO:0000070--P:mitotic sister chromatid segregation GO:0030473--P:nuclear migration along microtubule GO:0051258--P:protein polymerization GO:0046677--P:response to antibiotic
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