dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003972
Uniprot Accession P02283; H2B_DROME; Q4ABE1; Q9W5U7;
Genbank Protein ID NP_001027283.1; NP_001027287.1; NP_001027291.1; NP_001027296.1; NP_001027300.1; NP_001027305.1; NP_001027310.1; NP_001027315.1; NP_001027320.1; NP_001027325.1; NP_001027330.1; NP_001027335.1; NP_001027340.1; NP_001027345.1; NP_001027350.1; NP_001027355.1; NP_001027360.1; NP_001027365.1; NP_001027370.1; NP_001027375.1; NP_001027380.1; NP_001027385.1; NP_724342.1;
Genbank Nucleotide ID NM_001032112.2; NM_001032116.2; NM_001032120.2; NM_001032125.2; NM_001032129.2; NM_001032134.2; NM_001032139.2; NM_001032144.2; NM_001032149.2; NM_001032154.2; NM_001032159.2; NM_001032164.2; NM_001032169.2; NM_001032174.2; NM_001032179.2; NM_001032184.2; NM_001032189.2; NM_001032194.2; NM_001032199.2; NM_001032204.2; NM_001032209.2; NM_001032214.2; NM_165381.4;
Protein Name Histone H2B
Protein Synonyms/Alias
Gene Name His2B:CG33910
Gene Synonyms/Alias CG17949;CG33868;CG33870;CG33872;CG33874;CG33876;CG33878;CG33880;CG33882;CG33884;CG33886;CG33888;CG33890;CG33892;CG33894;CG33896;CG33898;CG33900;CG33902;CG33904;CG33906;CG33908;CG33910;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
21GKAQKNITKTDKKKKcurated22817900
34KKRKRKESYAIYIYKdbPTM 3.0;Phospho.ELM 9.0;SysPTM 2.0;curated15143281; 16381945; 23193290; 18327897; 19366988; 22817900
Sequence
(Fasta)		MPPKTSGKAA KKAGKAQKNI TKTDKKKKRK RKESYAIYIY KVLKQVHPDT GISSKAMSIM 60
NSFVNDIFER IAAEASRLAH YNKRSTITSR EIQTAVRLLL PGELAKHAVS EGTKAVTKYT 120
SSK 124
Keyword

KW-0002--3D-structure
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0238--DNA-binding
KW-0325--Glycoprotein
KW-1017--Isopeptide bond
KW-0488--Methylation
KW-0544--Nucleosome core
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0832--Ubl conjugation
Interpro

IPR009072--Histone-fold
IPR007125--Histone_H2A/H2B/H3
IPR000558--Histone_H2B
PROSITE

PS00357--HISTONE_H2B
Pfam

PF00125--Histone
Gene Ontology

GO:0005811--C:lipid particle
GO:0000788--C:nuclear nucleosome
GO:0000786--C:nucleosome
GO:0003677--F:DNA binding
GO:0006334--P:nucleosome assembly