dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003873
Uniprot Accession P01120; RAS2_YEAST; D6W181; Q45U01;
Genbank Protein ID NP_014301.1;
Genbank Nucleotide ID NM_001182936.1;
Protein Name Ras-like protein 2
Protein Synonyms/Alias
Gene Name RAS2
Gene Synonyms/Alias ASC1;CTN5;GLC5;YNL098C;N2198;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 The S.cerevisiae Ras proteins modulate the activity of the adenylate cyclase catalytic subunit and therefore affect the biosynthesis of cyclic-AMP.
Phosphorylation Sites
 dbPAF PTMs: 26 (View all)
PositionPeptidesSourceReferences ( PMIDs )
33LTIQLTQSHFVDEYDcurated22369663
93LLVYSITSKSSLDELcurated23825934
165INVEEAFYTLARLVRcurated24603354; 23825934
166NVEEAFYTLARLVRDcurated24603354; 23825934
181EGGKYNKTLTENDNScurated25315811
188TLTENDNSKQTSQDTcurated25315811
191ENDNSKQTSQDTKGScurated20377248
192NDNSKQTSQDTKGSGcurated20377248
198TSQDTKGSGANSVPRdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 21126336; 19366988; 25704821;
202TKGSGANSVPRNSGGdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 17563356; 18407956; 16381945; 23193290; 19060867;
207ANSVPRNSGGHRKMSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 17563356; 18407956; 16381945; 23193290; 21177495;
214SGGHRKMSNAANGKNdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated11875433; 17287358; 17563356; 16381945; 23193290; 21177495;
224ANGKNVNSSTTVVNAdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated15665377; 18407956; 16381945; 23193290; 21126336; 20702584;
225NGKNVNSSTTVVNARdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21177495; 20702584; 19684113;
226GKNVNSSTTVVNARNdbPTM 3.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19060867; 19366988; 26040406;
227KNVNSSTTVVNARNAPhosphoGRID 2.0;PhosphoPep 2.0;curated20702584; 19823750; 19795423; 19060867; 26040406; 22369663;
235VVNARNASIESKTGLdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated11875433; 15665377; 17330950; 18407956; 16381945; 23193290;
238ARNASIESKTGLAGNdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated11875433; 15665377; 18407956; 16381945; 23193290; 17330950;
240NASIESKTGLAGNQAdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 17330950; 21177495; 21081558;
262DRTNIDNSTGQAGQAcurated24961812
Sequence
(Fasta)		MPLNKSNIRE YKLVVVGGGG VGKSALTIQL TQSHFVDEYD PTIEDSYRKQ VVIDDEVSIL 60
DILDTAGQEE YSAMREQYMR NGEGFLLVYS ITSKSSLDEL MTYYQQILRV KDTDYVPIVV 120
VGNKSDLENE KQVSYQDGLN MAKQMNAPFL ETSAKQAINV EEAFYTLARL VRDEGGKYNK 180
TLTENDNSKQ TSQDTKGSGA NSVPRNSGGH RKMSNAANGK NVNSSTTVVN ARNASIESKT 240
GLAGNQATNG KTQTDRTNID NSTGQAGQAN AQSANTVNNR VNNNSKAGQV SNAKQARKQQ 300
AAPGGNTSEA SKSGSGGCCI IS 323
Keyword

KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0342--GTP-binding
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0488--Methylation
KW-0547--Nucleotide-binding
KW-0564--Palmitate
KW-0597--Phosphoprotein
KW-0636--Prenylation
KW-1185--Reference proteome
Interpro

IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR001806--Small_GTPase
IPR020849--Small_GTPase_Ras
PROSITE

PS51421--RAS
Pfam

PF00071--Ras
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0007190--P:activation of adenylate cyclase activity
GO:0030437--P:ascospore formation
GO:0032258--P:CVT pathway
GO:0016236--P:macroautophagy
GO:0045762--P:positive regulation of adenylate cyclase activity
GO:2000222--P:positive regulation of pseudohyphal growth
GO:0000411--P:positive regulation of transcription by galactose
GO:0097271--P:protein localization to bud neck
GO:0032880--P:regulation of protein localization
GO:0001302--P:replicative cell aging
GO:0007264--P:small GTPase mediated signal transduction