dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003872
Uniprot Accession P01119; RAS1_YEAST; D6W2G2;
Genbank Protein ID NP_014744.1;
Genbank Nucleotide ID NM_001183520.1;
Protein Name Ras-like protein 1
Protein Synonyms/Alias
Gene Name RAS1
Gene Synonyms/Alias YOR101W;YOR3205W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 The S.cerevisiae Ras proteins modulate the activity of the adenylate cyclase catalytic subunit and therefore affect the biosynthesis of cyclic-AMP.
Phosphorylation Sites
 dbPAF PTMs: 20
PositionPeptidesSourceReferences ( PMIDs )
194NTNEIRDSELTSSATcurated19823750; 25315811
197EIRDSELTSSATADRPhosphoPep 2.0;curated19060867; 26040289
198IRDSELTSSATADREdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19060867; 19366988;
199RDSELTSSATADREKdbPTM 3.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19060867; 19366988; 26040289;
201SELTSSATADREKKNdbPTM 3.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 26040289; 22817900;
211REKKNNGSYVLDNSLcurated22369663; 22817900; 19823750; 24961812; 20377248
212EKKNNGSYVLDNSLTcurated19823750; 25315811
217GSYVLDNSLTNAGTGcurated24961812; 25315811
219YVLDNSLTNAGTGSSdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 19823750; 24961812
223NSLTNAGTGSSSKSAPhosphoPep 2.0;curated19060867; 22817900; 19823750; 20377248
225LTNAGTGSSSKSAVNPhosphoGRID 2.0;PHOSIDA;curated19823750; 19795423; 21081558; 22817900; 25521595; 25315811;
226TNAGTGSSSKSAVNHPhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;curated19823750; 19795423; 21081558; 19060867; 22817900; 24961812;
227NAGTGSSSKSAVNHNPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900; 19823750; 19795423; 24961812;
229GTGSSSKSAVNHNGEPHOSIDA;PhosphoPep 2.0;curated21081558; 19060867; 22817900; 19795423; 24961812; 25521595;
238VNHNGETTKRTDEKNPhosphoPep 2.019060867
260NEGNTKYSSNGNGNRcurated25315811
261EGNTKYSSNGNGNRScurated19823750
268SNGNGNRSDISRGNQPhosphoGRID 2.0;PhosphoPep 2.0;curated19684113; 19060867; 26040289; 22817900
271NGNRSDISRGNQNNAPhosphoGRID 2.0;PhosphoPep 2.0;curated19684113; 19060867; 26040289; 22817900; 19823750
281NQNNALNSRSKQSAEcurated25315811
Sequence
(Fasta)		MQGNKSTIRE YKIVVVGGGG VGKSALTIQF IQSYFVDEYD PTIEDSYRKQ VVIDDKVSIL 60
DILDTAGQEE YSAMREQYMR TGEGFLLVYS VTSRNSFDEL LSYYQQIQRV KDSDYIPVVV 120
VGNKLDLENE RQVSYEDGLR LAKQLNAPFL ETSAKQAINV DEAFYSLIRL VRDDGGKYNS 180
MNRQLDNTNE IRDSELTSSA TADREKKNNG SYVLDNSLTN AGTGSSSKSA VNHNGETTKR 240
TDEKNYVNQN NNNEGNTKYS SNGNGNRSDI SRGNQNNALN SRSKQSAEPQ KNSSANARKE 300
SSGGCCIIC
Keyword

KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0488--Methylation
KW-0547--Nucleotide-binding
KW-0564--Palmitate
KW-0636--Prenylation
KW-1185--Reference proteome
Interpro

IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR001806--Small_GTPase
IPR020849--Small_GTPase_Ras
PROSITE

PS51421--RAS
Pfam

PF00071--Ras
Gene Ontology

GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0007189--P:adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0045762--P:positive regulation of adenylate cyclase activity
GO:0097271--P:protein localization to bud neck
GO:0001302--P:replicative cell aging
GO:0007264--P:small GTPase mediated signal transduction