dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003862
Uniprot Accession P01094; IPA3_YEAST; D6VZZ6;
Genbank Protein ID NP_013899.1;
Genbank Nucleotide ID NM_001182680.1;
Protein Name Protease A inhibitor 3
Protein Synonyms/Alias Proteinase inhibitor I(A)3;Proteinase yscA-inhibitor;Saccharopepsin inhibitor;
Gene Name PAI3
Gene Synonyms/Alias YMR174C;YM8010.04C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Specific and potent inhibitor for yeast aspartic protease A (yscA). The proteinase acts as a folding template stabilizing the helical conformation in the inhibitor, which results in the potent and specific blockage of the proteolytic activity.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
15VSEIFQSSKEKLQGDdbPTM 3.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22369663; 22817900
Sequence
(Fasta)		MNTDQQKVSE IFQSSKEKLQ GDAKVVSDAF KKMASQDKDG KTTDADESEK HNYQEQYNKL 60
KGAGHKKE 69
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0062--Aspartic protease inhibitor
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0646--Protease inhibitor
KW-1185--Reference proteome
Interpro

IPR023223--DNA_polIII_IA3_alpha-helix
IPR008956--IA3_dom
IPR019507--Pai3
PROSITE
Pfam

PF10466--Inhibitor_I34
Gene Ontology

GO:0005773--C:vacuole
GO:0019828--F:aspartic-type endopeptidase inhibitor activity
GO:0004866--F:endopeptidase inhibitor activity
GO:0007039--P:protein catabolic process in the vacuole