dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003840
Uniprot Accession P00950; PMG1_YEAST; D6VX45; Q02117;
Genbank Protein ID NP_012770.1;
Genbank Nucleotide ID NM_001179718.1;
Protein Name Phosphoglycerate mutase 1
Protein Synonyms/Alias
Gene Name GPM1
Gene Synonyms/Alias GPM;YKL152C;YKL607;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also Catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
Phosphorylation Sites
 dbPAF PTMs: 18
PositionPeptidesSourceReferences ( PMIDs )
12VLVRHGQSEWNEKNLdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 20702584; 19823750; 19795423;
21WNEKNLFTGWVDVKLcurated22369663
49LLKEKKVYPDVLYTSPhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated19779198; 19060867; 22817900
54KVYPDVLYTSKLSRAPhosphoPep 2.019060867
55VYPDVLYTSKLSRAIcurated25315811
56YPDVLYTSKLSRAIQPhosphoPep 2.0;curated19060867; 22817900; 25315811; 19547744
64KLSRAIQTANIALEKPhosphoPep 2.019060867
90WRLNERHYGDLQGKDPhosphoPep 2.019060867
112FGEEKFNTYRRSFDVPhosphoPep 2.0;curated19060867; 19823750; 25521595
113GEEKFNTYRRSFDVPPhosphoPep 2.0;curated19060867; 25521595
116KFNTYRRSFDVPPPPdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 17330950; 17563356; 18407956; 16381945; 23193290;
127PPPPIDASSPFSQKGdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 20702584; 19779198;
128PPPIDASSPFSQKGDdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 17563356; 18407956; 16381945; 23193290; 17330950;
131IDASSPFSQKGDERYdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21177495; 11283598; 19060867;
173VIAKDLLSGKTVMIAPhosphoPep 2.019060867
176KDLLSGKTVMIAAHGPhosphoGRID 2.0;PhosphoPep 2.0;curated19779198; 19060867; 22817900; 25315811; 20377248
185MIAAHGNSLRGLVKHdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 19779198; 19060867; 19366988;
197VKHLEGISDADIAKLdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 19779198; 21081558;
Sequence
(Fasta)		MPKLVLVRHG QSEWNEKNLF TGWVDVKLSA KGQQEAARAG ELLKEKKVYP DVLYTSKLSR 60
AIQTANIALE KADRLWIPVN RSWRLNERHY GDLQGKDKAE TLKKFGEEKF NTYRRSFDVP 120
PPPIDASSPF SQKGDERYKY VDPNVLPETE SLALVIDRLL PYWQDVIAKD LLSGKTVMIA 180
AHGNSLRGLV KHLEGISDAD IAKLNIPTGI PLVFELDENL KPSKPSYYLD PEAAAAGAAA 240
VANQGKK 248
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0324--Glycolysis
KW-0413--Isomerase
KW-0496--Mitochondrion
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR001345--PG/BPGM_mutase_AS
IPR005952--Phosphogly_mut1
PROSITE

PS00175--PG_MUTASE
Pfam

PF00300--His_Phos_1
Gene Ontology

GO:0005829--C:cytosol
GO:0005758--C:mitochondrial intermembrane space
GO:0005739--C:mitochondrion
GO:0004619--F:phosphoglycerate mutase activity
GO:0006094--P:gluconeogenesis
GO:0006096--P:glycolytic process