dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0003838
Uniprot Accession P00937; TRPG_YEAST; D6VWZ2;
Genbank Protein ID NP_012711.1;
Genbank Nucleotide ID NM_001179776.1;
Protein Name Multifunctional tryptophan biosynthesis protein
Protein Synonyms/Alias
Gene Name TRP3
Gene Synonyms/Alias YKL211C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
2------MSVHAATNPdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 15665377; 21081558; 19366988;
117GEIVHGKTSPISHDNcurated22817900; 25315811; 19547744
210GTWEENKSSPSNSILcurated25315811
211TWEENKSSPSNSILDdbPTM 3.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988; 22369663
213EENKSSPSNSILDRIcurated22369663
395EPLVEVNSKEELQRAPhosphoGRID 2.019779198
444DVLLIALSGITTRDDdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19366988
Sequence
(Fasta)
MSVHAATNPI NKHVVLIDNY DSFTWNVYEY LCQEGAKVSV YRNDAITVPE IAALNPDTLL 60
ISPGPGHPKT DSGISRDCIR YFTGKIPVFG ICMGQQCMFD VFGGEVAYAG EIVHGKTSPI 120
SHDNCGIFKN VPQGIAVTRY HSLAGTESSL PSCLKVTAST ENGIIMGVRH KKYTVEGVQF 180
HPESILTEEG HLMIRNILNV SGGTWEENKS SPSNSILDRI YARRKIDVNE QSKIPGFTFQ 240
DLQSNYDLGL APPLQDFYTV LSSSHKRAVV LAEVKRASPS KGPICLKAVA AEQALKYAEA 300
GASAISVLTE PHWFHGSLQD LVNVRKILDL KFPPKERPCV LRKEFIFSKY QILEARLAGA 360
DTVLLIVKML SQPLLKELYS YSKDLNMEPL VEVNSKEELQ RALEIGAKVV GVNNRDLHSF 420
NVDLNTTSNL VESIPKDVLL IALSGITTRD DAEKYKKEGV HGFLVGEALM KSTDVKKFIH 480
ELCE 485
Keyword

KW-0028--Amino-acid biosynthesis
KW-0057--Aromatic amino acid biosynthesis
KW-0181--Complete proteome
KW-0315--Glutamine amidotransferase
KW-0456--Lyase
KW-0511--Multifunctional enzyme
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0822--Tryptophan biosynthesis

Interpro

IPR013785--Aldolase_TIM
IPR029062--Class_I_gatase-like
IPR017926--GATASE
IPR013798--Indole-3-glycerol_P_synth
IPR001468--Indole-3-GlycerolPSynthase_CS
IPR011060--RibuloseP-bd_barrel
IPR006221--TrpG/PapA_dom

PROSITE

PS51273--GATASE_TYPE_1
PS00614--IGPS

Pfam

PF00117--GATase
PF00218--IGPS

Gene Ontology

GO:0005950--C:anthranilate synthase complex
GO:0004049--F:anthranilate synthase activity
GO:0004425--F:indole-3-glycerol-phosphate synthase activity
GO:0016740--F:transferase activity
GO:0006541--P:glutamine metabolic process
GO:0000162--P:tryptophan biosynthetic process