dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0003837
Uniprot Accession P00931; TRP_YEAST; D6VUB2;
Genbank Protein ID NP_011489.1;
Genbank Nucleotide ID NM_001180891.1;
Protein Name Tryptophan synthase
Protein Synonyms/Alias
Gene Name TRP5
Gene Synonyms/Alias YGL026C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
168DERLELLSHIADSFVcurated22817900
344TFWEDFKSLYSYIGRcurated24961812
353YSYIGRPSSLHKAERcurated24961812
354SYIGRPSSLHKAERLcurated24961812
540SNSTGMFSPFEHDTSdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19366988
683RGDKDVQSVAEVLPKdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17563356; 18407956; 16381945; 23193290; 19366988; 22817900;
706LRFEEDPSA------curated22369663; 20377248; 25315811
Sequence
(Fasta)
MSEQLRQTFA NAKKENRNAL VTFMTAGYPT VKDTVPILKG FQDGGVDIIE LGMPFSDPIA 60
DGPTIQLSNT VALQNGVTLP QTLEMVSQAR NEGVTVPIIL MGYYNPILNY GEERFIQDAA 120
KAGANGFIIV DLPPEEALKV RNYINDNGLS LIPLVAPSTT DERLELLSHI ADSFVYVVSR 180
MGTTGVQSSV ASDLDELISR VRKYTKDTPL AVGFGVSTRE HFQSVGSVAD GVVIGSKIVT 240
LCGDAPEGKR YDVAKEYVQG ILNGAKHKVL SKDEFFAFQK ESLKSANVKK EILDEFDENH 300
KHPIRFGDFG GQYVPEALHA CLRELEKGFD EAVADPTFWE DFKSLYSYIG RPSSLHKAER 360
LTEHCQGAQI WLKREDLNHT GSHKINNALA QVLLAKRLGK KNVIAETGAG QHGVATATAC 420
AKFGLTCTVF MGAEDVRRQA LNVFRMRILG AKVIAVTNGT KTLRDATSEA FRFWVTNLKT 480
TYYVVGSAIG PHPYPTLVRT FQSVIGKETK EQFAAMNNGK LPDAVVACVG GGSNSTGMFS 540
PFEHDTSVKL LGVEAGGDGV DTKFHSATLT AGRPGVFHGV KTYVLQDSDG QVHDTHSVSA 600
GLDYPGVGPE LAYWKSTGRA QFIAATDAQA LLGFKLLSQL EGIIPALESS HAVYGACELA 660
KTMKPDQHLV INISGRGDKD VQSVAEVLPK LGPKIGWDLR FEEDPSA 708
Keyword

KW-0028--Amino-acid biosynthesis
KW-0057--Aromatic amino acid biosynthesis
KW-0181--Complete proteome
KW-0456--Lyase
KW-0597--Phosphoprotein
KW-0663--Pyridoxal phosphate
KW-1185--Reference proteome
KW-0822--Tryptophan biosynthesis

Interpro

IPR013785--Aldolase_TIM
IPR011060--RibuloseP-bd_barrel
IPR006653--Trp_synth_b_CS
IPR006654--Trp_synth_beta
IPR023026--Trp_synth_beta/beta-like
IPR018204--Trp_synthase_alpha_AS
IPR002028--Trp_synthase_suA
IPR001926--TrpB-like_PLP-dep

PROSITE

PS00167--TRP_SYNTHASE_ALPHA
PS00168--TRP_SYNTHASE_BETA

Pfam

PF00291--PALP
PF00290--Trp_syntA

Gene Ontology

GO:0030170--F:pyridoxal phosphate binding
GO:0004834--F:tryptophan synthase activity
GO:0000162--P:tryptophan biosynthetic process