dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0003836
Uniprot Accession P00927; THDH_YEAST; D3DLZ2;
Genbank Protein ID NP_011009.1;
Genbank Nucleotide ID NM_001178977.1;
Protein Name Threonine dehydratase, mitochondrial
Protein Synonyms/Alias Threonine deaminase;
Gene Name ILV1
Gene Synonyms/Alias YER086W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
498VPNERIISFEFPERPcurated22369663
Sequence
(Fasta)
MSATLLKQPL CTVVRQGKQS KVSGLNLLRL KAHLHRQHLS PSLIKLHSEL KLDELQTDNT 60
PDYVRLVLRS SVYDVINESP ISQGVGLSSR LNTNVILKRE DLLPVFSFKL RGAYNMIAKL 120
DDSQRNQGVI ACSAGNHAQG VAFAAKHLKI PATIVMPVCT PSIKYQNVSR LGSQVVLYGN 180
DFDEAKAECA KLAEERGLTN IPPFDHPYVI AGQGTVAMEI LRQVRTANKI GAVFVPVGGG 240
GLIAGIGAYL KRVAPHIKII GVETYDAATL HNSLQRNQRT PLPVVGTFAD GTSVRMIGEE 300
TFRVAQQVVD EVVLVNTDEI CAAVKDIFED TRSIVEPSGA LSVAGMKKYI STVHPEIDHT 360
KNTYVPILSG ANMNFDRLRF VSERAVLGEG KEVFMLVTLP DVPGAFKKMQ KIIHPRSVTE 420
FSYRYNEHRH ESSSEVPKAY IYTSFSVVDR EKEIKQVMQQ LNALGFEAVD ISDNELAKSH 480
GRYLVGGASK VPNERIISFE FPERPGALTR FLGGLSDSWN LTLFHYRNHG ADIGKVLAGI 540
SVPPRENLTF QKFLEDLGYT YHDETDNTVY QKFLKY 577
Keyword

KW-0021--Allosteric enzyme
KW-0028--Amino-acid biosynthesis
KW-0100--Branched-chain amino acid biosynthesis
KW-0181--Complete proteome
KW-0412--Isoleucine biosynthesis
KW-0456--Lyase
KW-0496--Mitochondrion
KW-0663--Pyridoxal phosphate
KW-1185--Reference proteome
KW-0677--Repeat
KW-0809--Transit peptide

Interpro

IPR001721--ACT-like_dom
IPR000634--Ser/Thr_deHydtase_PyrdxlP-BS
IPR005787--Thr_deHydtase_biosynth
IPR001926--TrpB-like_PLP-dep

PROSITE

PS51672--ACT_LIKE
PS00165--DEHYDRATASE_SER_THR

Pfam

PF00291--PALP
PF00585--Thr_dehydrat_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005739--C:mitochondrion
GO:0004794--F:L-threonine ammonia-lyase activity
GO:0030170--F:pyridoxal phosphate binding
GO:0009097--P:isoleucine biosynthetic process
GO:0006567--P:threonine catabolic process