dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0003808
Uniprot Accession P00729; CBPY_YEAST; D6W0C4;
Genbank Protein ID NP_014026.1;
Genbank Nucleotide ID NM_001182806.1;
Protein Name Carboxypeptidase Y
Protein Synonyms/Alias
Gene Name PRC1
Gene Synonyms/Alias YMR297W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
257DFHIAGESYAGHYIPcurated22369663
Sequence
(Fasta)
MKAFTSLLCG LGLSTTLAKA ISLQRPLGLD KDVLLQAAEK FGLDLDLDHL LKELDSNVLD 60
AWAQIEHLYP NQVMSLETST KPKFPEAIKT KKDWDFVVKN DAIENYQLRV NKIKDPKILG 120
IDPNVTQYTG YLDVEDEDKH FFFWTFESRN DPAKDPVILW LNGGPGCSSL TGLFFELGPS 180
SIGPDLKPIG NPYSWNSNAT VIFLDQPVNV GFSYSGSSGV SNTVAAGKDV YNFLELFFDQ 240
FPEYVNKGQD FHIAGESYAG HYIPVFASEI LSHKDRNFNL TSVLIGNGLT DPLTQYNYYE 300
PMACGEGGEP SVLPSEECSA MEDSLERCLG LIESCYDSQS VWSCVPATIY CNNAQLAPYQ 360
RTGRNVYDIR KDCEGGNLCY PTLQDIDDYL NQDYVKEAVG AEVDHYESCN FDINRNFLFA 420
GDWMKPYHTA VTDLLNQDLP ILVYAGDKDF ICNWLGNKAW TDVLPWKYDE EFASQKVRNW 480
TASITDEVAG EVKSYKHFTY LRVFNGGHMV PFDVPENALS MVNEWIHGGF SL 533
Keyword

KW-0002--3D-structure
KW-0121--Carboxypeptidase
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0732--Signal
KW-0926--Vacuole
KW-0865--Zymogen

Interpro

IPR029058--AB_hydrolase
IPR001563--Peptidase_S10
IPR018202--Peptidase_S10_AS
IPR008442--Propeptide_carboxypepY

PROSITE

PS00560--CARBOXYPEPT_SER_HIS
PS00131--CARBOXYPEPT_SER_SER

Pfam

PF05388--Carbpep_Y_N
PF00450--Peptidase_S10

Gene Ontology

GO:0000324--C:fungal-type vacuole
GO:0004185--F:serine-type carboxypeptidase activity
GO:0046938--P:phytochelatin biosynthetic process
GO:0007039--P:protein catabolic process in the vacuole