dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003795
Uniprot Accession P00549; KPYK1_YEAST; D6VPH8; Q2VQG5;
Genbank Protein ID NP_009362.1;
Genbank Nucleotide ID NM_001178183.1;
Protein Name Pyruvate kinase 1
Protein Synonyms/Alias
Gene Name CDC19
Gene Synonyms/Alias PYK1;YAL038W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 43 (View all)
PositionPeptidesSourceReferences ( PMIDs )
8MSRLERLTSLNVVAGdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 18407956; 16381945; 23193290; 21126336; 20702584;
9SRLERLTSLNVVAGSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated15665377; 17287358; 17330950; 17563356; 18407956; 16381945;
16SLNVVAGSDLRRTSIdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19779198; 19060867; 19366988;
21AGSDLRRTSIIGTIGdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;curated17563356; 16381945; 23193290; 21126336; 19060867; 22817900;
22GSDLRRTSIIGTIGPdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated15665377; 17330950; 17563356; 18407956; 16381945; 23193290;
26RRTSIIGTIGPKTNNdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.018407956; 16381945; 23193290; 19779198; 19366988
31IGTIGPKTNNPETLVPhosphoGRID 2.0;UniProt;curated19779198; 26040289; 22817900; 25315811
53NIVRMNFSHGSYEYHdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17287358; 18407956; 16381945; 23193290; 19366988; 26040289;
56RMNFSHGSYEYHKSVdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated17287358; 16381945; 23193290; 19366988; 22369663; 22817900;
62GSYEYHKSVIDNARKPhosphoGRID 2.0;PhosphoPep 2.0;curated19823750; 19795423; 19060867; 22817900; 25315811
70VIDNARKSEELYPGRPhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated19779198; 19060867; 22817900; 24961812; 25521595; 25315811
74ARKSEELYPGRPLAIPhosphoPep 2.019060867
85PLAIALDTKGPEIRTcurated25315811
92TKGPEIRTGTTTNDVcurated25315811
184KGVNLPGTDVDLPALPhosphoGRID 2.0;UniProt;curated19779198; 11283598; 22817900; 24961812
192DVDLPALSEKDKEDLPhosphoGRID 2.0;curated19779198; 11283598; 22369663; 22817900; 24961812
213GVHMVFASFIRTANDdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 19060867; 19366988; 22369663;
223RTANDVLTIREVLGEcurated22817900; 19547744
257FDEILKVTDGVMVARcurated25315811
287QKKLIAKSNLAGKPVcurated26040289
Sequence
(Fasta)		MSRLERLTSL NVVAGSDLRR TSIIGTIGPK TNNPETLVAL RKAGLNIVRM NFSHGSYEYH 60
KSVIDNARKS EELYPGRPLA IALDTKGPEI RTGTTTNDVD YPIPPNHEMI FTTDDKYAKA 120
CDDKIMYVDY KNITKVISAG RIIYVDDGVL SFQVLEVVDD KTLKVKALNA GKICSHKGVN 180
LPGTDVDLPA LSEKDKEDLR FGVKNGVHMV FASFIRTAND VLTIREVLGE QGKDVKIIVK 240
IENQQGVNNF DEILKVTDGV MVARGDLGIE IPAPEVLAVQ KKLIAKSNLA GKPVICATQM 300
LESMTYNPRP TRAEVSDVGN AILDGADCVM LSGETAKGNY PINAVTTMAE TAVIAEQAIA 360
YLPNYDDMRN CTPKPTSTTE TVAASAVAAV FEQKAKAIIV LSTSGTTPRL VSKYRPNCPI 420
ILVTRCPRAA RFSHLYRGVF PFVFEKEPVS DWTDDVEARI NFGIEKAKEF GILKKGDTYV 480
SIQGFKAGAG HSNTLQVSTV 501
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0021--Allosteric enzyme
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0324--Glycolysis
KW-0418--Kinase
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0630--Potassium
KW-0670--Pyruvate
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR001697--Pyr_Knase
IPR015813--Pyrv/PenolPyrv_Kinase-like_dom
IPR011037--Pyrv_Knase-like_insert_dom
IPR015794--Pyrv_Knase_a/b
IPR018209--Pyrv_Knase_AS
IPR015793--Pyrv_Knase_brl
IPR015795--Pyrv_Knase_C
IPR015806--Pyrv_Knase_insert_dom
PROSITE

PS00110--PYRUVATE_KINASE
Pfam

PF00224--PK
PF02887--PK_C
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0016301--F:kinase activity
GO:0000287--F:magnesium ion binding
GO:0030955--F:potassium ion binding
GO:0004743--F:pyruvate kinase activity
GO:0006096--P:glycolytic process
GO:0006090--P:pyruvate metabolic process