dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003790
Uniprot Accession P00528; SRC64_DROME; A4V1H7; O18372; Q9VZA2;
Genbank Protein ID NP_001014561.1; NP_001014562.1; NP_001014563.1; NP_001014564.1; NP_001189051.1; NP_001246628.1; NP_001246629.1; NP_524934.2;
Genbank Nucleotide ID NM_001014561.2; NM_001014562.3; NM_001014563.3; NM_001014564.3; NM_001202122.1; NM_001259699.2; NM_001259700.2; NM_080195.4;
Protein Name Tyrosine-protein kinase Src64B
Protein Synonyms/Alias
Gene Name Src64B
Gene Synonyms/Alias Src1;CG7524;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 May play a role in the development of neural tissue and smooth muscle.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
306FYGKWRNSIDVAVKTdbPTM 3.0;SysPTM 2.018327897; 16381945; 23193290; 19366988
434RVIADDEYCPKQGSRdbPTM 3.0;Phospho.ELM 9.01281305; 16381945; 23193290
547SVTSEVPYREVQD--dbPTM 3.0;Phospho.ELM 9.01281305; N.N.; 16381945; 23193290
Sequence
(Fasta)		MGNKCCSKRQ DQELALAYPT GGYKKSDYTF GQTHINSSGG GNMGGVLGQK HNNGGSLDSR 60
YTPDPNHRGP LKIGGKGGVD IIRPRTTPTG VPGVVLKRVV VALYDYKSRD ESDLSFMKGD 120
RMEVIDDTES DWWRVVNLTT RQEGLIPLNF VAEERSVNSE DWFFENVLRK EADKLLLAEE 180
NPRGTFLVRP SEHNPNGYSL SVKDWEDGRG YHVKHYRIKP LDNGGYYIAT NQTFPSLQAL 240
VMAYSKNALG LCHILSRPCP KPQPQMWDLG PELRDKYEIP RSEIQLLRKL GRGNFGEVFY 300
GKWRNSIDVA VKTLREGTMS TAAFLQEAAI MKKFRHNRLV ALYAVCSQEE PIYIVQEYMS 360
KGSLLDFLRE GDGRYLHFED LIYIATQVAS GMEYLESKQL IHRDLAARNV LIGENNVAKI 420
CDFGLARVIA DDEYCPKQGS RFPVKWTAPE AIIYGKFSIK SDVWSYGILL MELFTYGQVP 480
YPGMHSREVI ENIERGFRMP KPTNHYFPDN IYQLLLQCWD AVPEKRPTFE FLNHYFESFS 540
VTSEVPYREV QD 553
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0656--Proto-oncogene
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
Gene Ontology

GO:0005829--C:cytosol
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0045172--C:germline ring canal
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030036--P:actin cytoskeleton organization
GO:0034332--P:adherens junction organization
GO:0007411--P:axon guidance
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0007349--P:cellularization
GO:0007391--P:dorsal closure
GO:0090136--P:epithelial cell-cell adhesion
GO:0007301--P:female germline ring canal formation
GO:0008302--P:female germline ring canal formation, actin assembly
GO:0008335--P:female germline ring canal stabilization
GO:0036058--P:filtration diaphragm assembly
GO:0007293--P:germarium-derived egg chamber formation
GO:0030708--P:germarium-derived female germ-line cyst encapsulation
GO:0045087--P:innate immune response
GO:0007254--P:JNK cascade
GO:0030717--P:karyosome formation
GO:0007611--P:learning or memory
GO:0007616--P:long-term memory
GO:0016319--P:mushroom body development
GO:0045886--P:negative regulation of synaptic growth at neuromuscular junction
GO:0008355--P:olfactory learning
GO:0048477--P:oogenesis
GO:0007424--P:open tracheal system development
GO:0030723--P:ovarian fusome organization
GO:0007300--P:ovarian nurse cell to oocyte transport
GO:0030046--P:parallel actin filament bundle assembly
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0018108--P:peptidyl-tyrosine phosphorylation
GO:0045860--P:positive regulation of protein kinase activity
GO:0006468--P:protein phosphorylation
GO:0008064--P:regulation of actin polymerization or depolymerization
GO:0042127--P:regulation of cell proliferation
GO:0007435--P:salivary gland morphogenesis
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway