dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003774
Uniprot Accession P00445; SODC_YEAST; D6VWS3; Q68HB2;
Genbank Protein ID NP_012638.1;
Genbank Nucleotide ID NM_001181762.1;
Protein Name Superoxide dismutase [Cu-Zn]
Protein Synonyms/Alias
Gene Name SOD1
Gene Synonyms/Alias YJR104C;J1968;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Phosphorylation Sites
 dbPAF PTMs: 20
PositionPeptidesSourceReferences ( PMIDs )
15LKGDAGVSGVVKFEQdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 19779198; 19366988; 22817900
24VVKFEQASESEPTTVdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21126336; 19779198; 21081558;
26KFEQASESEPTTVSYdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated18407956; 16381945; 23193290; 19060867; 19366988; 26040289;
29QASESEPTTVSYEIAPhosphoPep 2.0;curated19060867; 22369663; 22817900; 25315811
30ASESEPTTVSYEIAGPhosphoPep 2.0;curated19060867; 22817900
32ESEPTTVSYEIAGNSPhosphoPep 2.0;curated19060867; 22817900
33SEPTTVSYEIAGNSPPhosphoPep 2.0;curated19060867; 22817900; 25315811
39SYEIAGNSPNAERGFdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated15665377; 17563356; 18407956; 16381945; 23193290; 21177495;
71HFNPFKKTHGAPTDEcurated25315811
76KKTHGAPTDEVRHVGPhosphoPep 2.019060867
90GDMGNVKTDENGVAKPhosphoPep 2.019060867
99ENGVAKGSFKDSLIKdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 17563356; 18407956; 16381945; 23193290; 21177495;
103AKGSFKDSLIKLIGPdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;curated18407956; 16381945; 23193290; 21177495; 19823750; 19779198;
111LIKLIGPTSVVGRSVPhosphoPep 2.019060867
112IKLIGPTSVVGRSVVdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;curated17287358; 16381945; 23193290; 19779198; 19060867; 19366988;
117PTSVVGRSVVIHAGQdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 19779198; 19060867; 19366988;
132DDLGKGDTEESLKTGdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17287358; 16381945; 23193290; 19779198; 19060867; 19366988;
135GKGDTEESLKTGNAGcurated20377248
138DTEESLKTGNAGPRPPhosphoGRID 2.0;PhosphoPep 2.0;UniProt;curated19779198; 19060867; 22817900
153ACGVIGLTN------PhosphoPep 2.019060867
Sequence
(Fasta)		MVQAVAVLKG DAGVSGVVKF EQASESEPTT VSYEIAGNSP NAERGFHIHE FGDATNGCVS 60
AGPHFNPFKK THGAPTDEVR HVGDMGNVKT DENGVAKGSF KDSLIKLIGP TSVVGRSVVI 120
HAGQDDLGKG DTEESLKTGN AGPRPACGVI GLTN 155
Keyword

KW-0002--3D-structure
KW-0049--Antioxidant
KW-0181--Complete proteome
KW-0186--Copper
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-1015--Disulfide bond
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0496--Mitochondrion
KW-0560--Oxidoreductase
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0832--Ubl conjugation
KW-0862--Zinc
Interpro

IPR024134--SOD_Cu/Zn_/chaperone
IPR018152--SOD_Cu/Zn_BS
IPR001424--SOD_Cu_Zn_dom
PROSITE

PS00087--SOD_CU_ZN_1
PS00332--SOD_CU_ZN_2
Pfam

PF00080--Sod_Cu
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005758--C:mitochondrial intermembrane space
GO:0005634--C:nucleus
GO:0005507--F:copper ion binding
GO:0004784--F:superoxide dismutase activity
GO:0008270--F:zinc ion binding
GO:0001320--P:age-dependent response to reactive oxygen species involved in chronological cell aging
GO:0006878--P:cellular copper ion homeostasis
GO:0006882--P:cellular zinc ion homeostasis
GO:0031505--P:fungal-type cell wall organization
GO:1901856--P:negative regulation of cellular respiration
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0036091--P:positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0050821--P:protein stabilization
GO:0019430--P:removal of superoxide radicals
GO:0006801--P:superoxide metabolic process