dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003729
Uniprot Accession O96881; O96881_DROME;
Genbank Protein ID NP_523923.1;
Genbank Nucleotide ID NM_079199.3;
Protein Name Transcription initiation factor IIE subunit beta
Protein Synonyms/Alias
Gene Name TfIIEbeta
Gene Synonyms/Alias TfIIE-beta;CG1276;Dmel_CG1276;
Organism Drosophila melanogaster(Fruit fly)
NCBI Taxa ID 7227
Functional Description
(View all)		 Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
40PPPPSDDSRRKMRPPcurated22817900
Sequence
(Fasta)		MDPALLRERE AFKKRAMATP TVEKKSKPDR PAPPPPSDDS RRKMRPPNAP RLDATTYKTM 60
SGSSQYRFGV LAKIVKFMRT RHQDGDDHPL TIDEILDETN QLDIGQSVKN WLASEALHNN 120
PKVEASPCGT KFSFKPVYKI KDGKTLMRLL KQHDLKGLGG ILLDDVQESL PHCEKVLKNR 180
SAEILFVVRP IDKKKILFYN DRTANFSVDD EFQKLWRSAT VDAMDDAKID EYLEKQGIRS 240
MQDHGLKKAI PKRKKAANKK RQFKKPRDNE HLADVLEVYE DNTLTLKGVN PT 293
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR016656--TFIIE-bsu
IPR003166--TFIIE_bsu_DNA-bd
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS51351--TFIIE_BETA_C
Pfam

PF02186--TFIIE_beta
Gene Ontology

GO:0005634--C:nucleus
GO:0005673--C:transcription factor TFIIE complex
GO:0003677--F:DNA binding
GO:0022008--P:neurogenesis
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006367--P:transcription initiation from RNA polymerase II promoter