| Tag |
Content |
| dbPAF ID |
dbPAF-0003330 |
| Uniprot Accession |
O94742; SEM1_YEAST; D6VSZ2;
|
| Genbank Protein ID |
NP_010651.3;
|
| Genbank Nucleotide ID |
NM_001184328.3;
|
| Protein Name |
26S proteasome complex subunit SEM1 |
| Protein Synonyms/Alias |
|
| Gene Name |
SEM1 |
| Gene Synonyms/Alias |
DSH1;YDR363W-A; |
| Organism |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast) |
| NCBI Taxa ID |
559292 |
Functional Description
(View all) |
Versatile protein that might stabilize multiple protein complexes involved in diverse pathways. Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Associates also with the TREX-2 complex that is required for transcription-coupled mRNA export, and the COP9 signalosome, which is involved in deneddylation.Functional Description
Versatile protein that might stabilize multiple protein complexes involved in diverse pathways. Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Associates also with the TREX-2 complex that is required for transcription-coupled mRNA export, and the COP9 signalosome, which is involved in deneddylation. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MSTDVAAAQA QSKIDLTKKK NEEINKKSLE EDDEFEDFPI DTWANGETIK SNAVTQTNIW 60
EENWDDVEVD DDFTNELKAE LDRYKRENQ
Fasta Sequence
>O94742|SEM1|Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
MSTDVAAAQAQSKIDLTKKKNEEINKKSLEEDDEFEDFPIDTWANGETIKSNAVTQTNIWEENWDDVEVDDDFTNELKAELDRYKRENQ
|
| Keyword |
KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0804--Transcription
|
| Interpro |
IPR007834--DSS1_SEM1
|
| PROSITE |
|
| Pfam |
PF05160--DSS1_SEM1
|
| Gene Ontology |
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0008541--C:proteasome regulatory particle, lid subcomplex
GO:0034515--C:proteasome storage granule
GO:0000724--P:double-strand break repair via homologous recombination
GO:0006887--P:exocytosis
GO:0030447--P:filamentous growth
GO:0016578--P:histone deubiquitination
GO:0035753--P:maintenance of DNA trinucleotide repeats
GO:0006406--P:mRNA export from nucleus
GO:0043248--P:proteasome assembly
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051726--P:regulation of cell cycle
GO:0072742--P:SAGA complex localization to transcription regulatory region
GO:0006351--P:transcription, DNA-templated
GO:0006511--P:ubiquitin-dependent protein catabolic process
|
