Tag |
Content |
dbPAF ID |
dbPAF-0003057 |
Uniprot Accession |
O88498; B2L11_RAT; O88497; Q9WUI8; |
Genbank Protein ID |
NP_072134.1; NP_741985.1; NP_741986.1; |
Genbank Nucleotide ID |
NM_022612.1; NM_171988.2; NM_171989.1; |
Protein Name |
Bcl-2-like protein 11 |
Protein Synonyms/Alias |
|
Gene Name |
Bcl2l11 |
Gene Synonyms/Alias |
Bim;Bod; |
Organism |
Rattus norvegicus(Rat) |
NCBI Taxa ID |
10116 |
Functional Description (View all) |
Induces apoptosis and anoikis.Functional Description
Induces apoptosis and anoikis.
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Phosphorylation Sites
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dbPAF PTMs: 8 |
Sequence (Fasta) | MAKQPSDVNS ECDREGGQLQ PAERPPQLRP GAPTSLQTES QGNPDGEGDR CPHGSPQGPL 60 APPASPGPFA TRSPLFIFVR RSSLLSRSSS GYFSFDTDRS PAPMSCDKST QTPSPPCQAF 120 NHYLSAMASI RQSQEEPEDL RPEIRIAQEL RRIGDEFNET YTRRAFANDY REAEDHPQMV 180 ILQLLRFIFR LVWRRH
197Fasta Sequence
>O88498|Bcl2l11|Rattus norvegicus(Rat) MAKQPSDVNSECDREGGQLQPAERPPQLRPGAPTSLQTESQGNPDGEGDRCPHGSPQGPLAPPASPGPFATRSPLFIFVRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASIRQSQEEPEDLRPEIRIAQELRRIGDEFNETYTRRAFANDYREAEDHPQMVILQLLRFIFRLVWRRH
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Keyword |
KW-0024--Alternative initiation KW-0025--Alternative splicing KW-0053--Apoptosis KW-0181--Complete proteome KW-0472--Membrane KW-0496--Mitochondrion KW-0597--Phosphoprotein KW-1185--Reference proteome KW-0832--Ubl conjugation
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Interpro |
IPR014771--Apoptosis_Bim_N IPR017288--Bcl-2-like_11 IPR015040--Bcl-x_interacting_BH3_dom
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PROSITE |
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Pfam |
PF08945--Bclx_interact PF06773--Bim_N
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Gene Ontology |
GO:0097141--C:BIM-BCL-2 complex GO:0097140--C:BIM-BCL-xl complex GO:0005829--C:cytosol GO:0019898--C:extrinsic component of membrane GO:0005874--C:microtubule GO:0005739--C:mitochondrion GO:0008017--F:microtubule binding GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process GO:1902263--P:apoptotic process involved in embryonic digit morphogenesis GO:0001783--P:B cell apoptotic process GO:0001782--P:B cell homeostasis GO:0007420--P:brain development GO:0007160--P:cell-matrix adhesion GO:0060154--P:cellular process regulating host cell cycle in response to virus GO:0048066--P:developmental pigmentation GO:0043583--P:ear development GO:0097192--P:extrinsic apoptotic signaling pathway in absence of ligand GO:0001701--P:in utero embryonic development GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage GO:0001822--P:kidney development GO:0008584--P:male gonad development GO:0030879--P:mammary gland development GO:0002262--P:myeloid cell homeostasis GO:0042475--P:odontogenesis of dentin-containing tooth GO:0043065--P:positive regulation of apoptotic process GO:0060139--P:positive regulation of apoptotic process by virus GO:0045787--P:positive regulation of cell cycle GO:0010942--P:positive regulation of cell death GO:2000271--P:positive regulation of fibroblast apoptotic process GO:2001244--P:positive regulation of intrinsic apoptotic signaling pathway GO:1902110--P:positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:0043525--P:positive regulation of neuron apoptotic process GO:0032464--P:positive regulation of protein homooligomerization GO:0090200--P:positive regulation of release of cytochrome c from mitochondria GO:0048563--P:post-embryonic organ morphogenesis GO:0048070--P:regulation of developmental pigmentation GO:0046620--P:regulation of organ growth GO:0034976--P:response to endoplasmic reticulum stress GO:0007283--P:spermatogenesis GO:0048536--P:spleen development GO:0043029--P:T cell homeostasis GO:0070242--P:thymocyte apoptotic process GO:0048538--P:thymus development GO:0035148--P:tube formation
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