dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0003050 |
| Uniprot Accession | O88480; CABIN_RAT; |
| Genbank Protein ID | NP_446027.2; |
| Genbank Nucleotide ID | NM_053575.2; |
| Protein Name | Calcineurin-binding protein cabin-1 |
| Protein Synonyms/Alias | Calcineurin inhibitor;CAIN; |
| Gene Name | Cabin1 |
| Gene Synonyms/Alias | |
| Organism | Rattus norvegicus(Rat) |
| NCBI Taxa ID | 10116 |
| Functional Description (View all) |
May be required for replication-independent chromatin assembly (By similarity). May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MIRIAALNAS STIEDDHEGS FKSHKIQTKE AQEAEAFALY HKALDLQKHD RFEESAKAYH 60 ELLEARLLRE AVSSGDEKEG LKHPGLILKY STYKNLAQLA AQREDLETAM EFYLEAVMLD 120 STDVNLWYKI GHVALRLIRL PLARHAFEEG LRCNPDHWPC LDNLITVLYT LSDYTTCLYF 180 ICKALEKDCR YSKGLVLKEK IFEEQPCLRK DSLRMFLKCD MSVHEVSVNA AETQAIVDEA 240 LGLRKKRQAL IVREKEPDLK LVQPIPFFTW KCLGESLLAM YNHLTTCEPP RPSLGKRIDL 300 SDYQDPSQLL APSIVVTPVS VVQPSPVCTN PTVAVAEPVL SYTSVTTTSF PLHSPGLLDT 360 GTPMGDVSGG DKSKKGVKRK KTLEESGETA KRRSARVRNT KCKKEEKVDF QGLLVKFLPS 420 RLRKLDPEEE DDPFNNYEVQ SEAKLESFSN VGPHRLSFDS ATFMESEKQD VHAFLMENLT 480 NGGVLELMMR YLKSMGHKFL LKWPPGLAEV VLSVYHSWRR HSTSLPNPLL RDCSNKHIKD 540 MMLMSLSCME LQLDQWLLTK GRSSTVSPRN CPAGVVTGRF GPDFPGTHCL GDLLQLSFAS 600 SQRDLFEDGW LEFVVRVYWL KARFLALQGD MEQALENYDI CTEILQSSTA LQAQAGAEQR 660 DIVIRLPNLH NDSIVSLEEI DKNLKSLERC QSLEEIQRLF EAGDYKAVVQ LLRPTLCTSG 720 FDRAKHLEFM TSIPERPAQL LLLQDSLLRL EEHRQCFECS DVALNEAVQQ MLNSSDSAAK 780 EEWAATVTQL LLGMEQALSS DSRGSILKES SSPTGLVRLT NNLIQVIDCS MAVQEEPKEP 840 YVSSVLPWII LHRIIWQEED TFRSLCHQQQ LQNPTEEGIS EMPMLPSSLM LLNTAHEYLG 900 RRSWCCNSDG ALLRFYVHVL QKELAASASE DTHPYKEELE TALEQCFYCL YSFPSKKSKA 960 RYLEEHSAQQ VDLTWEDALF MFEYFKPKTL PEFDSYKTST VSADLANLLK RIATIVPRTE 1020 KPALSMDKVS AYIEGTSAEV PCLPDGADPA PPVLNELYYL LADYHFKNKE QSKAIKFYMH 1080 DICICPNRFD SWAGMALARA SRIQDKLNSN ELKSDGPIWR HATPVLNCFR RALEIDSSNL 1140 SLWIEYGTMS YALHSFASRQ LKQWRAELPP EVVQQMEDRR DSMLETARHC FTSAAHCEGD 1200 GDEEEWLIHY MLGKVAEKQQ QPPTVYLLHY RQAGHYLHEE AARYPKKIHY HNPPELAMEA 1260 LEVYFRLHAS ILKLLGKPDS GVSAEVLVSF MKEAAEGPFA RGEEKNTPKA SEKEKACLVD 1320 EDSHSSAGTL PGPGASLPSS SGPGLTSPPY TATPIDHDYV KCKKPRQQAT PDDRSQDSTA 1380 VALSDSSSTQ DFFNEPTSLL DGSRKLLPEK RISGLSAQAG PSGKDLPGPT EERGKTEESL 1440 ESTEAFRVVE PSVQKPVADS SASAYIPSKP AVSTPPPWDG KKRSDPLGEP VAFPQGLPAG 1500 AEEQRQFLTE QCIASFCLCL SRFPQHYKSL YRLAFLYTYS KTHRNLQWAR DVLLGSSIPW 1560 QQLQHMPAQG LFCERNKTNF FNGIWRIPVD EIDRPGSFAW HMNRSIVLLL KVLAQLRDHS 1620 TLLKVSSMLQ RTPDQGKKYL RDADRQVLAQ RAFILTVKVL EDTLSELAEG LEHPGSKACG 1680 LSGARMTTDV SHKASPEDGQ ESLPHPKKLP LADGSGPGPE PGGKVGPLHQ LPVATDTRDN 1740 TEQGGEPKDK ERPPVGPTEP MDTGETAARH PDLEPTPRLL PGRPPRDRGP ESRSAELSLE 1800 ELSISTRQQP APLVPSPVTP TTAAPTTMGA RAAGHPEEAP PRPNRKRKLL QDTESGKTLL 1860 LDAYRVWQQG QKAMAYDLSR IEKIMSETYM LIKQVDEETA LEQAVKFCQV HLGAAAQRQA 1920 SGDAPTTPKH PKDSRENFFP ATVAPSAPDT TAPDALQRPS DSHLKPGLAA AITCPPSASA 1980 STPDPGIPQP HRPEAVPSRA PLSPDGEEVS GVTEGPSFLS QEPRHSHQMK MAATGPLAEQ 2040 HCWPVEAACQ TGAEPTFSQA TSTKVPSSGS TQTPESHQGK TESSRAKSRL LPNMPKLVIP 2100 SATTKFPPEI TVTPPTPTLL SPKGSISEET KQKLKSAILS AQSAANVRKE SLCQPALEVL 2160 ETSSQESSLE SETDEDDDFM DV 2183 |
| Keyword | KW-0156--Chromatin regulator |
| Interpro | IPR015134--MEF2_binding |
| PROSITE | |
| Pfam | |
| Gene Ontology | GO:0005737--C:cytoplasm |