dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003033
Uniprot Accession O88422; GALT5_RAT;
Genbank Protein ID NP_113984.1;
Genbank Nucleotide ID NM_031796.1;
Protein Name Polypeptide N-acetylgalactosaminyltransferase 5
Protein Synonyms/Alias Polypeptide GalNAc transferase 5;GalNAc-T5;pp-GaNTase 5;Protein-UDP acetylgalactosaminyltransferase 5;UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5;
Gene Name Galnt5
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward EA2 peptide substrate, but has a weak activity toward Muc2, Muc1b, rMuc-2 or mG-Muc substrates.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
359IPRSQSQTLSSPLAPcurated22276854
361RSQSQTLSSPLAPKRcurated22276854
Sequence
(Fasta)		MNKIRKFFRG SGRVLAFIFV ASVIWLLFDM AALRLSFSEI NTGILKEDIM RREQTGFRVE 60
ADQMTILSPS SRGMRPPRNG AGGKESFRKA ENRVLKVEEN VDQVQRKGKM QFLLGRGKAV 120
SLWHRTHVQT LPVTLPMQKT QGRDSKPEVS SLHMMSKQTT VLGSEKDSFT VSRGVPLNKT 180
AEHTETLDKK QEAPENYNLS SDTSKQASQR ALNVTISVRT DRSKQQSQTV TKSSIQFASL 240
PILKPEEVTV TKKTEAQGKD LKYEAHKARP LLKFTADVGH LKKQSTNETG LGVLPEADGA 300
KVAPGKKLNF SESQIVIITK EEGQKTDTKE VPNSKIQTVF PKLLGESQGK HIPRSQSQTL 360
SSPLAPKRAV SQSKPTLAEE LHTARSNLTA KATTVGHQQS HANISENPGK HHVLRIDVTL 420
SPRDLNAPGQ FGRPVVVPPG KKKEAEQRWK EGNFNVYLSD LIPVDRAIED TRPAGCAEQL 480
VHNDLPTTSI IMCFVDEVWS ALLRSVHSVL NRSPPHLIKE ILLVDDFSTK DYLKANLDKY 540
MSQFPKVRIL RLKERHGLIR ARLAGAQNAT GDVLTFLDSH VECNVGWLEP LLERVYLNRK 600
KVACPVIEVI NDKDMSYMTV DNFQRGVFTW PMNFGWRTIP PDVIAKNGIK ETDIIRCPVM 660
AGGLFSIDKS YFYELGTYDP GLDVWGGENM ELSFKVWMCG GEIEIIPCSR VGHIFRNDNP 720
YSFPKDRMKT VERNLVRVAE VWLDEYKELF YGHGDHLIDQ GLDVGNLTQQ RELRKKLKCQ 780
SFKWYLDNVF PDLKAPVVRA SGVFINLALG KCVSIKNITV VLEDCDGSSE LQQFNYTWVR 840
LIKHGEWCVA PIPDKGSLTL YPCDNRNNRL KWLHRSASAF HPELVDHIVF ESYQQLLCME 900
GNFSQKTLKL AACNPTEPQQ KWKFEKYYDV 931
Keyword

KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0328--Glycosyltransferase
KW-0333--Golgi apparatus
KW-0430--Lectin
KW-0464--Manganese
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0735--Signal-anchor
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR001173--Glyco_trans_2-like
IPR029044--Nucleotide-diphossugar_trans
IPR000772--Ricin_B_lectin
PROSITE

PS50231--RICIN_B_LECTIN
Pfam

PF00535--Glycos_transf_2
PF00652--Ricin_B_lectin
Gene Ontology

GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0030246--F:carbohydrate binding
GO:0046872--F:metal ion binding
GO:0004653--F:polypeptide N-acetylgalactosaminyltransferase activity
GO:0006486--P:protein glycosylation