dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003023
Uniprot Accession O88377; PI42B_RAT;
Genbank Protein ID NP_446002.1;
Genbank Nucleotide ID NM_053550.1;
Protein Name Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
Protein Synonyms/Alias 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta;Diphosphoinositide kinase 2-beta;Phosphatidylinositol 5-phosphate 4-kinase type II beta;PI(5)P 4-kinase type II beta;PIP4KII-beta;Phosphatidylinositol-phosphate kinase IIgamma;PIPKIIgamma;PtdIns(5)P-4-kinase isoform 2-beta;
Gene Name Pip4k2b
Gene Synonyms/Alias Pip5k2b;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
17AVAVAPLSASKTKTKcurated23984901
Sequence
(Fasta)		MSSNCTSTTA VAVAPLSASK TKTKKKHFVC QKVKLFRASE PILSVLMWGV NHTINELSNV 60
PVPVMLMPDD FKAYSKIKVD NHLFNKENLP SRFKFKEYCP MVFRNLRERF GIDDQDYQNS 120
VTRSAPINSD SQGRCGTRFL TTYDRRFVIK TVSSEDVAEM HNILKKYHQF IVECHGNTLL 180
PQFLGMYRLT VDGVETYMVV TRNVFSHRLT VHRKYDLKGS TVAREASDKE KAKDLPTFKD 240
NDFLNEGQKL RVGEESKKNF LEKLKRDVEF LAQLKIMDYS LLVGIHDVDR AEQEETEVED 300
RAEEEECEND GVGGGLLCSY GTPPDSPGNL LSFPRFFGPG EFDPSVDVYA MKSHESAPKK 360
EVYFMAIIDI LTPYDAKKKA AHAAKTVKHG AGAEISTVNP EQYSKRFNEF MSNILT 417
Keyword

KW-0007--Acetylation
KW-0067--ATP-binding
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0418--Kinase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0832--Ubl conjugation
Interpro

IPR027483--PInositol-4-P-5-kinase_C
IPR002498--PInositol-4-P-5-kinase_core
IPR027484--PInositol-4-P-5-kinase_N
IPR016034--PInositol-4P-5-kinase_core_sub
PROSITE

PS51455--PIPK
Pfam

PF01504--PIP5K
Gene Ontology

GO:0005776--C:autophagosome
GO:0005789--C:endoplasmic reticulum membrane
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0016308--F:1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0016309--F:1-phosphatidylinositol-5-phosphate 4-kinase activity
GO:0005524--F:ATP binding
GO:2000786--P:positive regulation of autophagosome assembly