dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0003022
Uniprot Accession O88370; PI42C_RAT;
Genbank Protein ID NP_536728.2;
Genbank Nucleotide ID NM_080480.2;
Protein Name Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Protein Synonyms/Alias Phosphatidylinositol 5-phosphate 4-kinase type II gamma;PI(5)P 4-kinase type II gamma;PIP4KII-gamma;
Gene Name Pip4k2c
Gene Synonyms/Alias Pip5k2c;
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)		 May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
5---MASSSVPPATAPdbPTM 3.0;PhosphoSitePlus;SysPTM 2.016641100; 16381945; 23193290; 22135298; 19366988
10SSSVPPATAPAAAGGSysPTM 2.016641100; 19366988
26GPGFGFASKTKKKHFSysPTM 2.016641100; 19366988
28GFGFASKTKKKHFVQSysPTM 2.016641100; 19366988
253LNKNQKVYIGEEEKKPhosphoSitePlus22135298
Sequence
(Fasta)		MASSSVPPAT APAAAGGPGP GFGFASKTKK KHFVQQKVKV FRAADPLVGV FLWGVAHSIN 60
ELSQVPPPVM LLPDDFKASS KIKVNNHLFH RENLPSHFKF KEYCPQVFRN LRDRFAIDDH 120
DYLVSLTRSP PSETEGSDGR FLISYDRTLV IKEVSSEDIA DMHSNLSNYH QYIVKCHGNT 180
LLPQFLGMYR VSVENEDSYM LVMRNMFSHR LPVHRKYDLK GSLVSREASD KEKVKELPTL 240
KDMDFLNKNQ KVYIGEEEKK VFLEKLKRDV EFLVQLKIMD YSLLLGIHDI IRGSEPEEEG 300
PVREEESEWD GDCNLTGPPA LVGSYGTSPE GIGGYIHSHR PLGPGEFESF IDVYAIRSAE 360
GAPEGGVFHG LIDILTQYDA KKKAAHAAKT VKHGAGAEIS TVHPEQYAKR FLDFISNIFA 420
421
Keyword

KW-0007--Acetylation
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0418--Kinase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
Interpro

IPR023610--PInositol-4-P-5-kinase
IPR027483--PInositol-4-P-5-kinase_C
IPR002498--PInositol-4-P-5-kinase_core
IPR027484--PInositol-4-P-5-kinase_N
IPR016034--PInositol-4P-5-kinase_core_sub
PROSITE

PS51455--PIPK
Pfam

PF01504--PIP5K
Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016020--C:membrane
GO:0016308--F:1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0016309--F:1-phosphatidylinositol-5-phosphate 4-kinase activity
GO:0005524--F:ATP binding
GO:0006661--P:phosphatidylinositol biosynthetic process
GO:0046854--P:phosphatidylinositol phosphorylation