dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0002997
Uniprot Accession O88202; LPP60_RAT; Q4G088;
Genbank Protein ID NP_653351.1;
Genbank Nucleotide ID NM_144750.2;
Protein Name 60 kDa lysophospholipase
Protein Synonyms/Alias
Gene Name Aspg
Gene Synonyms/Alias
Organism Rattus norvegicus(Rat)
NCBI Taxa ID 10116
Functional Description
(View all)
Exhibits lysophospholipase, transacylase, PAF acetylhydrolase and asparaginase activities.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
24GGTIGMRSEGGVLVPdbPTM 3.0;PhosphoSitePlus;curated17567059; 16381945; 23193290; 22135298; 22817900
Sequence
(Fasta)
MARATGPEQR LLAIYTGGTI GMRSEGGVLV PGRGLAAVLR TLHMLHDEEY ARAHSLPEDT 60
LVLPPASSDQ RIIYKVLECQ PLFDSSDMTI TEWVQIAQTI ERHYTQYQGF VVIHGTDTMA 120
FAASVLSFML ENLQKPVILT GAQVPIHELW SDGRENLLGA LLMAGQYVIP EVCLFFQNQL 180
FRGNRTTKVD ARRFAAFCSP NLPPLATVGA DVTINRELVR KASWKSHLVV HSNMEPDVGL 240
LRLYPGIPAS LVRTFLQPPL KGVVMETFGS GNGPTKPDLI QELRAAAERG LIIVNCTHCL 300
QGAVTSDYAP GMAMAGAGII SGFDMTSEAA LAKLSYVLGQ PGLSLSDRKK LLAKDLRGEM 360
TLPTTDDLLG DDMLGCRATW LLSMNGSQDA DAMKDVLLPG LALAAAHAGD LDTLQAFVEL 420
GRDLNLKDYS GQTPLHVAAR RGHASVVAML LQKGVDVDAC NEDGQSPLLL AVRGRHQSVI 480
RLLRAAGAHL SPQELEDVGT ELCRLASRAD SEGLRAWWQA GADLGQPDYD GHCALQVAEA 540
AGNADVVALL QSLEDRVSAQ PQPH 565
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR006033--AsnASEI
IPR006034--Asparaginase/glutaminase
IPR027475--Asparaginase/glutaminase_AS2
IPR027473--L-asparaginase_C
IPR027474--L-asparaginase_N

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS00917--ASN_GLN_ASE_2
PS51732--ASN_GLN_ASE_3

Pfam

PF12796--Ank_2
PF00710--Asparaginase

Gene Ontology

GO:0003847--F:1-alkyl-2-acetylglycerophosphocholine esterase activity
GO:0004067--F:asparaginase activity
GO:0004622--F:lysophospholipase activity
GO:0006528--P:asparagine metabolic process
GO:0016042--P:lipid catabolic process
GO:0006644--P:phospholipid metabolic process